353 results found
    1. Neuroscience

    Functionally asymmetric motor neurons contribute to coordinating locomotion of Caenorhabditis elegans

    Oleg Tolstenkov et al.
    The 'missing' class of Caenorhabditis elegans excitatory motor neurons, AS, contribute to propagation and coordination of body waves, integrating information from, and feeding back to premotor interneurons byelectrical signaling.
    1. Neuroscience

    Monosynaptic premotor circuit tracing reveals neural substrates for oro-motor coordination

    Edward Stanek IV et al.
    Retrograde tracing of the neural circuits that control movement of the jaw and tongue reveals how shared premotor neurons help to ensure coordinated muscle activity.
    1. Neuroscience

    Mild myelin disruption elicits early alteration in behavior and proliferation in the subventricular zone

    Elizabeth A Gould et al.
    Mild myelin disruption leads to early axonal pathology, a novel pathological response in neural stem cells, regionally increased oligodendrocytes and altered behavior.
    1. Neuroscience

    Adaptation after vastus lateralis denervation in rats demonstrates neural regulation of joint stresses and strains

    Cristiano Alessandro et al.
    The adaptation strategy used by the nervous system following muscle paralysis restores task performance while minimizing the stresses and strains within a joint.
    1. Neuroscience

    Quantification of gait parameters in freely walking wild type and sensory deprived Drosophila melanogaster

    César S Mendes et al.
    Novel imaging experiments suggest that fruit flies modify their neural circuitry for walking at slow, medium and fast speeds, and that proprioception is not essential for coordinated walking.
    1. Biochemistry and Chemical Biology

    Ataxin-1 oligomers induce local spread of pathology and decreasing them by passive immunization slows Spinocerebellar ataxia type 1 phenotypes

    Cristian A Lasagna-Reeves et al.
    Building on previous work (Lasagna-Reeves et al., 2015) it is shown that polyglutamine ATXN1 oligomers propagate locally in SCA1 mice, and that passive immunotherapy targeting soluble oligomers can lead to an improvement in motor coordination and a modest increase in life span.
    1. Neuroscience

    A quantitative framework for whole-body coordination reveals specific deficits in freely walking ataxic mice

    Ana S Machado et al.
    Analysis of 3D paw kinematics and whole-body coordination in freely walking mice isolates specific features of gait ataxia and supports the hypothesis that the cerebellum provides an internal forward model for motor control.
    1. Neuroscience

    Neurophysiology: Fruit flies step out

    Ronald L Calabrese
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    1. Structural Biology and Molecular Biophysics

    Molecular Motors: Small steps and giant leaps

    Bram Prevo, Erwin JG Peterman
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