910 results found
    1. Neuroscience

    Output variability across animals and levels in a motor system

    Angela Wenning et al.
    Population output variability in a motor control system varies across levels (CPG, motor neurons, muscles) and can be ascribed to life history differences among animals and in some cases to differences between bilaterally homologous elements.
    1. Neuroscience

    A neural circuit mechanism for regulating vocal variability during song learning in zebra finches

    Jonathan Garst-Orozco et al.
    By demonstrating song learning-related synaptic strengthening and pruning in the vocal control circuits of songbirds, and showing how such changes can reduce the sensitivity of the circuit to ‘noisy’ inputs, a simple neural circuit mechanism for regulating motor variability during motor skill learning is identified.
    1. Neuroscience

    Motor Systems: Variability in neural networks

    Daniel R Kick, David J Schulz
    Experiments on neurons in the heart system of the leech reveal why rhythmic behaviors differ between individuals.
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    1. Neuroscience

    Corticostriatal dynamics encode the refinement of specific behavioral variability during skill learning

    Fernando J Santos et al.
    Recordings from the mouse brain as animals learn a lever pressing task reveal how the motor system optimizes skill learning by reducing variability in those aspects of task performance that are essential for achieving a goal.
    1. Neuroscience

    Mechanisms and functional roles of glutamatergic synapse diversity in a cerebellar circuit

    Valeria Zampini et al.
    Unipolar brush cells within the cerebellum show highly variable responses to input from the inner ear, and this variability boosts the learning of motor skills.
    1. Cell Biology
    2. Ecology

    The Natural History of Model Organisms: From molecular manipulation of domesticated Chlamydomonas reinhardtii to survival in nature

    Severin Sasso et al.
    Dubbed the 'green yeast', the model alga C. reinhardtii has profoundly advanced many areas of biology, but much remains to be learnt about its life in the wild.
    1. Neuroscience

    Chemotaxis: Cider vinegar rules

    Ronald L Calabrese
    Experiments in wind tunnels have shed light on the rules that govern how flies respond when they detect odors.
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    1. Cell Biology

    Ragulator and GATOR1 complexes promote fission yeast growth by attenuating TOR complex 1 through Rag GTPases

    Kim Hou Chia et al.
    The Rag-family GTPases, known activators of TOR complex 1 (TORC1), also function as attenuator that prevents deregulated hyperactivation of TORC1 signaling.
    1. Cell Biology
    2. Computational and Systems Biology

    Principles of cellular resource allocation revealed by condition-dependent proteome profiling

    Eyal Metzl-Raz et al.
    Steadily growing cells prepare for conditions that demand increased translation by producing excess ribosomes, at the expense of lower steady-state growth rate.
    1. Neuroscience

    Risk of punishment influences discrete and coordinated encoding of reward-guided actions by prefrontal cortex and VTA neurons

    Junchol Park, Bita Moghaddam
    Risk of punishment during reward seeking behavior is associated with a functional "disconnection" of the PFC-VTA circuit due to a transient loss of VTA-driven theta oscillation.

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