22 results found
    1. Computational and Systems Biology
    2. Genetics and Genomics

    A metabolic modeling-based framework for predicting trophic dependencies in native rhizobiomes of crop plants

    Alon Avraham Ginatt, Maria Berihu ... Shiri Freilich
    Understanding metabolic interactions and successive cross-feeding in native microbiomes illuminates the mechanisms behind plant disease promotion and suppression, enhancing our ability to manipulate microbiomes toward specific functions of interest.
    1. Microbiology and Infectious Disease

    Adaptation of CD4 in gorillas and chimpanzees conveyed resistance to simian immunodeficiency viruses

    Cody J. Warren, Arturo Barbachano-Guerrero ... Sara L. Sawyer
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    • Convincing
    1. Cell Biology

    High-altitude hypoxia exposure inhibits erythrophagocytosis by inducing macrophage ferroptosis in the spleen

    Wan-ping Yang, Mei-qi Li ... Qian-qian Luo
    Hypobaric hypoxia exposure initiates splenic ferroptosis, reducing red pulp macrophages and exacerbating high-altitude polycythemia by impairing erythrophagocytosis and increasing red blood cell retention.
    1. Evolutionary Biology
    2. Immunology and Inflammation

    The molecular mechanism and evolutionary divergence of caspase 3/7-regulated gasdermin E activation

    Hang Xu, Zihao Yuan ... Li Sun
    Functional divergence of caspase 3 and 7 in vertebrate is mediated by key residue mutation.
    1. Microbiology and Infectious Disease

    A coordinated transcriptional switching network mediates antigenic variation of human malaria parasites

    Xu Zhang, Francesca Florini ... Kirk W Deitsch
    Malaria parasites avoid destruction by their host's immune response through systematic and coordinated expression switching between members of a network of variant antigen-encoding genes, a process that is mediated by a uniquely conserved gene called var2csa.
    1. Ecology
    2. Evolutionary Biology

    Mountain gorillas maintain strong affiliative biases for maternal siblings despite high male reproductive skew and extensive exposure to paternal kin

    Nicholas M Grebe, Jean Paul Hirwa ... Stacy Rosenbaum
    Mountain gorillas, who live in close-knit social groups with siblings and non-siblings of both sexes throughout their lives, show distinct behavioral biases towards maternal versus paternal kin.
    1. Evolutionary Biology

    Transition to siblinghood causes a substantial and long-lasting increase in urinary cortisol levels in wild bonobos

    Verena Behringer, Andreas Berghänel ... Gottfried Hohmann
    In wild bonobos, sibling birth induced a sudden increase in urinary cortisol levels in the older offspring, a physiological response that occurred in all subjects and was independent of their age.
    1. Evolutionary Biology

    New fossils of Australopithecus sediba reveal a nearly complete lower back

    Scott A Williams, Thomas Cody Prang ... Lee R Berger
    Newly recovered lumbar vertebrae belonging to Malapa Hominin 2, an adult female of the fossil hominin species Australopithecus sediba, demonstrate that this individual was adapted to upright posture and bipedal locomotion but also had adaptations for climbing in trees.
  1. Ben Barres Spotlight Awards: Announcing the winners for 2021

    10 researchers have been recognised with awards to catalyse change and unlock new opportunities for their research and careers.

Refine your results by:

Type
Research categories