Studies of the house mouse Mus musculus have provided important insights into mammalian biology, and efforts to study wild house mice and to create new inbred strains from wild populations have the potential to increase its usefulness as a model system.

The three main types of inhibitory neurons in mouse primary visual cortex respond differently to locomotion in darkness and during visual stimulation, revealing context-dependent responses to changes in behavioral state.

High-resolution, large-scale immunohistochemical mouse brain images showing global views of different brain regions, as well as cellular and subcellular details, identified distinct localization of PKA RIβ and RIIβ regulatory subunits that reveal functional differences.

Post-implantation epiblast maturation and patterning of anterior-posterior axis in mouse embryonic development are mediated by pluripotency transcription factor Zfp281 through transcriptional and epigenetic control of Nodal signaling.

Single embryo RNA-seq combined with mouse genetics provides a comprehensive view on the roles of Rlim and Xist for the regulation of X-linked gene expression during early mouse embryogenesis.

A panel of seven new mouse strains with chromosomal duplications is used to identify a minimal genetic region required in three copies to cause congenital heart defects typical of human Down syndrome.

Native state dynamics of mouse prion protein were measured, and these motions were shown to be having a role in initiation of aggregation.

Robust and wide-spread locomotion-related neural signals, revealed in the mouse auditory midbrain, suggest that integrating movement-related information is an essential aspect of midbrain sound processing.

A realistic model of the connections between local populations of neurons in the adult mouse brain can be constructed based on just two biologically plausible rules.

Glutamatergic brainstem neurons drive motor and respiratory deficits, and GABAergic basal ganglia neurons cause hypothermia and fatal epileptic events, in a model of mitochondrial disease.