3,697 results found
    1. Neuroscience

    Forebrain deletion of the dystonia protein torsinA causes dystonic-like movements and loss of striatal cholinergic neurons

    Samuel S Pappas et al.
    Conditional forebrain deletion of Tor1a generates a dystonia model with face, construct, and predictive validity, and demonstrates that striatal cholinergic interneurons are selectively vulnerable to loss of the dystonia protein torsinA.
    1. Developmental Biology

    Intrinsic control of muscle attachment sites matching

    Alexandre Carayon et al.
    Making a link between deletion of transcription cis-regulatory elements by CrispR/Cas9, obtention of mutants with single muscle morphology defects and their impact on locomotion.
    1. Neuroscience

    Hippocampal theta coordinates memory processing during visual exploration

    James E Kragel et al.
    Eye movements time-locked to retrieval and novelty during learning preferentially occur at distinct phases of hippocampal theta.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Structure and transport mechanism of the sodium/proton antiporter MjNhaP1

    Cristina Paulino et al.
    The inward-open and outward-open structures of MjNhaP1 explain the mechanism of electroneutral sodium-proton antiport across the cell membrane.
    1. Neuroscience

    Electrocorticographic dissociation of alpha and beta rhythmic activity in the human sensorimotor system

    Arjen Stolk et al.
    Direct cortical recordings in humans link the spectral structure of local field potentials to inhibition/disinhibition mechanisms coordinating sensorimotor neuronal populations during movement imagery.
    1. Structural Biology and Molecular Biophysics

    Ribosome structures to near-atomic resolution from thirty thousand cryo-EM particles

    Xiao-chen Bai et al.
    A combination of direct-electron detectors and statistical movie processing allows ribosome cryo-EM structures to be determined to resolutions that were previously only attainable by X-ray crystallography.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Coalescing beneficial host and deleterious antiparasitic actions as an antischistosomal strategy

    John D Chan et al.
    Engagement of both host and parasite signaling pathways proves a novel approach for developing improved anti-parasitic therapies.
    1. Structural Biology and Molecular Biophysics

    Conserved mechanisms of microtubule-stimulated ADP release, ATP binding, and force generation in transport kinesins

    Joseph Atherton et al.
    Cryo-electron microscopy reconstructions of two microtubule-bound transport kinesins at 7 Å resolution reveal how microtubule track binding stimulates ADP release, primes the active site for ATP binding and enables force generation.
    1. Neuroscience

    Decision and navigation in mouse parietal cortex

    Michael Krumin et al.
    When mice use vision to choose their trajectories, a large fraction of parietal cortex activity can be precisely predicted from navigational attributes such as spatial position and heading.
    1. Structural Biology and Molecular Biophysics
    2. Chromosomes and Gene Expression

    The mechanism of variability in transcription start site selection

    Libing Yu et al.
    Variability in bacterial transcription start site selection involves DNA “scrunching” and “anti-scrunching,” which may represent a general mechanism for start site selection in all organisms.

Refine your results by:

Type
Research categories