7 results found
    1. Chromosomes and Gene Expression

    Maturation of selected human mitochondrial tRNAs requires deadenylation

    Sarah F Pearce et al.
    Removal of spurious poly(A) tails by the PDE12 exoribonuclease is required to maintain the integrity of human mitochondrial tRNAs and rRNAs and their availability for efficient mitochondrial translation.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Motility precedes egress of malaria parasites from oocysts

    Dennis Klug, Friedrich Frischknecht
    A surface protein triggers intra-oocyst motility of Plasmodium sporozoites to ensure parasite egress from oocysts.
    1. Cancer Biology
    2. Cell Biology

    ERG signaling in prostate cancer is driven through PRMT5-dependent methylation of the Androgen Receptor

    Zineb Mounir et al.
    The transcription factor ERG recruits the PRMT5 enzyme to methylate the androgen receptor, presenting a post-translational regulatory mechanism that could be therapeutically exploited to control cell proliferation.
    1. Immunology and Inflammation

    Antigen receptor control of methionine metabolism in T cells

    Linda V Sinclair et al.
    Antigen receptor control of methionine transport is critical to co-ordinate protein synthesis and the production of methyl donors for nucleotide and protein methylations which are required for T cell differentiation.
    1. Chromosomes and Gene Expression
    2. Genetics and Genomics

    Nuclear genetic regulation of the human mitochondrial transcriptome

    Aminah T Ali et al.
    Common nuclear genetic variants are associated with fundamental biological processes occurring in human mitochondria and potentially point to novel roles for nuclear genes in transcriptional regulation of the mitochondrial genome.
    1. Cancer Biology

    Different genetic mechanisms mediate spontaneous versus UVR-induced malignant melanoma

    Blake Ferguson et al.
    Genetic variation determines whether or not UV exposure accelerates melanoma development.
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Suppressor of cytokine signaling (SOCS)5 ameliorates influenza infection via inhibition of EGFR signaling

    Lukasz Kedzierski et al.
    The intracellular SOCS5 protein has a unique and key role in restraining influenza A infection by regulating epidermal growth factor receptor signaling in airway epithelial cells.

Refine your results by:

Type
Research categories