Under conditions where the force of HIV infection per cell is high, partial attenuation of infection with inhibitors can increase the number of live infected cells and may paradoxically be beneficial for viral spread.

The great pond snail is a multipurpose model organism and a contemporary choice for addressing a wide range of biological questions, problems and phenomena in the laboratory and the field.

The way that bacteria grow—either floating in liquid or attached to a surface—affects their ability to evolve antimicrobial resistance and our ability to treat infections.

Research in molecular ecology and evolution is increasingly utilizing the model plant Arabidopsis thaliana, placing a spotlight on its natural history.

Although questionable research practices inflate false positive rates, they have little effect on replicability because they also increase power.

Researchers should define in advance the criteria for excluding the results of experiments that 'did not work' from articles.

An analysis of more than 3000 randomized controlled trials published in JAMA, the Lancet and NEJM has identified 396 medical reversals.

20 emerging issues in bioengineering that will have profound impacts on society have been identified.

An international effort is needed to overcome the paywalls, customs regulations and lack of local suppliers that hinder research in low- and middle-income countries.