Under conditions where the force of HIV infection per cell is high, partial attenuation of infection with inhibitors can increase the number of live infected cells and may paradoxically be beneficial for viral spread.

The way that bacteria grow—either floating in liquid or attached to a surface—affects their ability to evolve antimicrobial resistance and our ability to treat infections.

Research in molecular ecology and evolution is increasingly utilizing the model plant Arabidopsis thaliana, placing a spotlight on its natural history.

An international effort is needed to overcome the paywalls, customs regulations and lack of local suppliers that hinder research in low- and middle-income countries.

An analysis of more than 3000 randomized controlled trials published in JAMA, the Lancet and NEJM has identified 396 medical reversals.

A compendium of critical genomic numbers for viruses through the lenses of different viral classification systems.

In the first study attempting to formally quantify the deleterious impact of research misconduct on funding sources and publication output, we found that misconduct accounts for a small but substantial portion of American biomedical science funding dollars and damages the productivity and rate of funding acquisition of those who commit misconduct.

Researchers should define in advance the criteria for excluding the results of experiments that 'did not work' from articles.

A new mouse model of sepsis can reproduce the long-term muscle weakness seen in patients who survive this life-threatening illness.