182 results found
    1. Neuroscience

    Ultra-Rapid serial visual presentation reveals dynamics of feedforward and feedback processes in the ventral visual pathway

    Yalda Mohsenzadeh et al.
    Reducing visibility with higher image presentation rates increases recurrent processing demands along the visual processing pathway to resolve object recognition.
    1. Neuroscience

    Stimulus vignetting and orientation selectivity in human visual cortex

    Zvi N Roth et al.
    Functional MRI measurements of orientation reflect coarse-scale biases that are wholly determined by second-order interactions between the stimulus aperture and the underlying orientation.
    1. Neuroscience

    Vision: Framing orientation selectivity

    Floris P de Lange, Matthias Ekman
    The ongoing debate on the neural basis of orientation selectivity in the primary visual cortex continues.
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    1. Human Biology and Medicine

    Research: Adequate statistical power in clinical trials is associated with the combination of a male first author and a female last author

    Willem M Otte et al.
    An analysis of 31,873 clinical trials shows that adequate statistical power was most often present in trials with a male first author and a female last author.
    1. Neuroscience

    Risk of punishment influences discrete and coordinated encoding of reward-guided actions by prefrontal cortex and VTA neurons

    Junchol Park, Bita Moghaddam
    Risk of punishment during reward seeking behavior is associated with a functional "disconnection" of the PFC-VTA circuit due to a transient loss of VTA-driven theta oscillation.
    1. Cancer Biology

    NFATc2 enhances tumor-initiating phenotypes through the NFATc2/SOX2/ALDH axis in lung adenocarcinoma

    Zhi-Jie Xiao et al.
    NFATc2 maintains the drug-induced TIC phenotypes through trans-activating SOX2/ALDH1A1 expression and scavenging stress from ROS.
    1. Neuroscience

    A theory of working memory without consciousness or sustained activity

    Darinka Trübutschek et al.
    Visual information can be maintained in non-conscious working memory for several seconds via short-term changes in synaptic weights.
    1. Developmental Biology

    Drosophila neprilysins control insulin signaling and food intake via cleavage of regulatory peptides

    Benjamin Hallier et al.
    The catalytic activity of a Drosophila neprilysin is critical to proper insulin expression and food intake by regulating homeostasis of distinct signaling peptides.
    1. Neuroscience

    Human blindsight is mediated by an intact geniculo-extrastriate pathway

    Sara Ajina et al.
    White matter microstructure in hemianopia patients indicates that blindsight requires an intact connection between the lateral geniculate nucleus and extrastriate cortex.
    1. Structural Biology and Molecular Biophysics

    Atomic structure of the 26S proteasome lid reveals the mechanism of deubiquitinase inhibition

    Corey M Dambacher et al.
    Within the isolated lid sub-complex of the proteasome, a finely tuned network of interactions maintains the deubiquitinase in an inhibited conformation; dramatic rearrangements of the lid subunits upon incorporation into the holoenzyme lead to the deubiquitinase’s activation.

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