89 results found
    1. Developmental Biology

    Neural tube-associated boundary caps are a major source of mural cells in the skin

    Gaspard Gerschenfeld, Fanny Coulpier ... Piotr Topilko
    Neural tube-associated boundary caps are heterogeneous with a non-neural crest-derived subpopulation that may originate from the developing meninges, which gives rise to derivatives that migrate along nerves to detach and differentiate into skin mural cells.
    1. Developmental Biology

    Proper migration of lymphatic endothelial cells requires survival and guidance cues from arterial mural cells

    Di Peng, Koji Ando ... Katarzyna Koltowska
    Spatio-temporal analysis using live imaging in zebrafish reveals mural cells as a source of pro-lymphangiogenic factors including chemokine and growth factor signalling, necessary for robust lymphatic endothelial cell migration and survival.
    1. Neuroscience

    Distinct signatures of calcium activity in brain mural cells

    Chaim Glück, Kim David Ferrari ... Bruno Weber
    Increases of extracellular potassium silence capillary pericyte calcium signaling, suggesting a participation of capillary pericytes in the potassium-mediated neurovascular communication.
    1. Cell Biology

    Identification of functionally distinct fibro-inflammatory and adipogenic stromal subpopulations in visceral adipose tissue of adult mice

    Chelsea Hepler, Bo Shan ... Rana K Gupta
    Fibro-inflammatory progenitors represent a subpopulation of perivascular cells in visceral adipose tissues of mice that promote inflammation and fibrosis.
    1. Medicine

    Directing visceral white adipocyte precursors to a thermogenic adipocyte fate improves insulin sensitivity in obese mice

    Chelsea Hepler, Mengle Shao ... Rana K Gupta
    Genetic inactivation of the transcription factor, Zfp423, in visceral white adipocyte precursors leads to the formation of thermogenic adipocytes in visceral fat depots and improves insulin sensitivity in obese mice.
    1. Developmental Biology

    Pericytes are progenitors for coronary artery smooth muscle

    Katharina S Volz, Andrew H Jacobs ... Kristy Red-Horse
    Progenitor cells for the muscle layer around the coronary arteries have been identified revealing a key step in how the embryo forms these important blood vessels.
    1. Neuroscience

    Brain endothelial cell TRPA1 channels initiate neurovascular coupling

    Pratish Thakore, Michael G Alvarado ... Scott Earley
    Activation of TRPA1 channels on cerebral capillary endothelial cells initiates a retrograde signal that propagates and dilates upstream arterioles.
    1. Developmental Biology

    A single-cell atlas of the cycling murine ovary

    Mary E Morris, Marie-Charlotte Meinsohn ... David Pépin
    A survey of the transcriptomic landscape of the mouse ovary at the single-cell level reveals both the cellular complexity of this organs and the dynamic nature of the cellular states that accompany estrous cycling.
    1. Developmental Biology
    2. Neuroscience

    Radial glia regulate vascular patterning around the developing spinal cord

    Ryota L Matsuoka, Michele Marass ... Didier YR Stainier
    Identification of a novel role for central nervous system-resident progenitors in the patterning of the vascular network around the developing spinal cord.

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