Adult muscle precursors (AMP) cells in Drosophila send out filopodia to interact with neighbouring muscles, which drive the reactivation of AMPs via an Insulin-Notch-Myc cascade.

A gradient of Mib1-Dll4 within multinucleated muscle fibers maintains a continuum of metastable states within the muscle stem cell pool during tissue homeostasis.

A user-friendly, and modular, 3D skeletal muscle culture assay enables iterative studies of murine muscle stem cell pool size regulation, functional heterogeneity, return to quiescence, and age-associated functional defects within a 96-well footprint.

Large flight muscle of Drosophila are made by the regulated amplification of a newly identified stem cell population.

Cellular and molecular analyses reveal how Myogenin controls muscle stem cell quiescence and growth of adult muscle fibres.

The protein Tristetraprolin promotes the decay of MyoD mRNA to maintain satellite cell quiescence.

Cell encapsulation-based transcriptional profiling using myogenic progenitors reveals that long-range factors in the aged systemic environment induce a wide range of signaling pathways in a niche-independent manner.

Modulation of muscle stem cell redox state in culture both improves their amplification while maintaining a similar grafting potential as freshly isolated stem cells.

Developing long bones contain distinct mesenchymal stem-cell populations derived from mesoderm and neural crest, which have specialized functions in skeleton formation and the establishment of the hematopoietic stem-cell niche, respectively.

While Notch activation dedifferentiates newly differentiated muscle cells; it improves the function of muscle fiber as a niche-supporting cell of muscle stem cells.