2,019 results found
    1. Neuroscience

    POMC neurons control fertility through differential signaling of MC4R in Kisspeptin neurons

    Rajae Talbi, Todd L Stincic ... Víctor M Navarro
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    Sensory experience controls dendritic structure and behavior by distinct pathways involving degenerins

    Sharon Inberg, Yael Iosilevskii ... Benjamin Podbilewicz
    Mechanosensory isolation of C. elegans nematodes independently induces homeostatic structural changes in the dendritic tree and differential response to mechanical stimulation, both these structural and behavioral outcomes are mediated by degenerins and do not affect presynaptic calcium dynamics.
    1. Biochemistry and Chemical Biology
    2. Developmental Biology

    Reduction of DNA Topoisomerase Top2 reprograms the epigenetic landscape and extends health and life span across species

    Man Zhu, Meng Ma ... Jing Yang
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    1. Genetics and Genomics
    2. Neuroscience

    Zinc finger homeobox-3 (ZFHX3) orchestrates genome-wide daily gene expression in the suprachiasmatic nucleus

    Akanksha Bafna, Gareth Banks ... Patrick M Nolan
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Interleukin-1 prevents SARS-CoV-2-induced membrane fusion to restrict viral transmission via induction of actin bundles

    Xu Zheng, Shi Yu ... Guangxun Meng
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    TRPV4 overactivation enhances cellular contractility and drives ocular hypertension in TGFβ2 overexpressing eyes

    Christopher N Rudzitis, Monika Lakk ... David Križaj
    Not revised
    Reviewed Preprint v1
    • Fundamental
    • Convincing
    1. Cell Biology

    Oxidized low-density lipoprotein potentiates angiotensin II-induced Gq activation through the AT1-LOX1 receptor complex: Implications for renal dysfunction

    Jittoku Ihara, Yibin Huang ... Koichi Yamamoto
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Solid
    1. Developmental Biology

    Mechanical forces pattern endocardial Notch activation via mTORC2-PKC pathway

    Yunfei Mu, Shijia Hu ... Hongjun Shi
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology
    2. Microbiology and Infectious Disease

    MftG is crucial for ethanol metabolism of mycobacteria by linking mycofactocin oxidation to respiration

    Ana Patrícia Graça, Vadim Nikitushkin ... Gerald Lackner
    Revised
    Reviewed Preprint v3
    Updated
    • Fundamental
    • Compelling
    1. Cell Biology
    2. Neuroscience

    Zebrafish live imaging reveals only around 2% rather than 50% of motor neurons die through apoptosis during early development

    Hao Jia, Hongmei Yang, Kathy Qian Luo
    Revised
    Reviewed Preprint v2
    Updated
    • Useful
    • Incomplete
    • Inadequate
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