3,144 results found
    1. Neuroscience

    Neuronal Detection Triggers Systemic Digestive Shutdown in Response to Adverse Food Sources

    Yating Liu, Guojing Tian ... Bin Qi
    Not revised
    Reviewed Preprint v1
    • Important
    • Convincing
    • Incomplete
    1. Structural Biology and Molecular Biophysics

    Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter

    Parveen Goyal, KanagaVijayan Dhanabalan ... Subramanian Ramaswamy
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Convincing
    1. Cell Biology

    Mechanisms of PP2A-Ankle2 dependent nuclear reassembly after mitosis

    Jingjing Li, Xinyue Wang ... Vincent Archambault
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology

    Mapping kinase domain resistance mechanisms for the MET receptor tyrosine kinase via deep mutational scanning

    Gabriella O Estevam, Edmond M Linossi ... James S Fraser
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Developmental Biology

    Meioc-Piwil1 complexes regulate rRNA transcription for differentiation of spermatogonial stem cells

    Toshihiro Kawasaki, Toshiya Nishimura ... Noriyoshi Sakai
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Convincing
    • Solid
    1. Developmental Biology

    Evolution of lateralized gustation in nematodes

    Marisa Mackie, Vivian Vy Le ... Ray L Hong
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Solid
    1. Immunology and Inflammation
    2. Microbiology and Infectious Disease

    Interleukin-1 prevents SARS-CoV-2-induced membrane fusion to restrict viral transmission via induction of actin bundles

    Xu Zheng, Shi Yu ... Guangxun Meng
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Biochemistry and Chemical Biology

    Alzheimer-mutant γ-secretase complexes stall amyloid β-peptide production

    Parnian Arafi, Sujan Devkota ... Michael S Wolfe
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    • Convincing
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Paradoxical dominant negative activity of an immunodeficiency-associated activating PIK3R1 variant

    Patsy R Tomlinson, Rachel G Knox ... Robert K Semple
    PIK3R1 mutations that cause immunodeficiency through PI3-kinase hyperactivation also cause SHORT syndrome, due to PI3-kinase hypofunction, attributable to PI3-kinase destabilisation and outcompetition by mutant PIK3R1.
    1. Microbiology and Infectious Disease

    Aeromonas hydrophila CobQ is a new type of NAD+- and Zn2+-independent protein lysine deacetylase

    Yuqian Wang, Guibin Wang ... Xiangmin Lin
    Revised
    Reviewed Preprint v3
    Updated
    • Valuable
    • Incomplete
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