37 results found
    1. Genetics and Genomics
    2. Neuroscience

    Antagonist actions of CMK-1/CaMKI and TAX-6/Calcineurin along the C. elegans thermal avoidance circuit orchestrate nociceptive habituation

    Martina Rudgalvyte, Zehan Hu ... Dominique A Glauser
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Negative cell cycle regulation by calcineurin is necessary for proper beta cell regeneration in zebrafish

    Laura Massoz, David Bergemann ... Isabelle Manfroid
    Calcineurin fine tunes the balance between proliferation and differentiation of Notch-responsive progenitors in the pancreatic ducts to enable beta cell regeneration in zebrafish.
    1. Cancer Biology

    The mitochondrial stress-induced protein carboxyl-terminal alanine and threonine tailing (msiCAT-tailing) promotes glioblastoma tumorigenesis by modulating mitochondrial functions

    Ting Cai, Bei Zhang ... Zhihao Wu
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology

    Eugenol mimics exercise to promote skeletal muscle fiber remodeling and myokine IL-15 expression by activating TRPV1 channel

    Tengteng Huang, Xiaoling Chen ... Zhiqing Huang
    Eugenol has the potential as a novel exercise mimetic, and TRPV1 may represent a promising target for the development of exercise mimetics.
    1. Immunology and Inflammation

    Early acquisition of S-specific Tfh clonotypes after SARS-CoV-2 vaccination is associated with the longevity of anti-S antibodies

    Xiuyuan Lu, Hiroki Hayashi ... Sho Yamasaki
    Clonotypic tracing of SARS-CoV-2–responsive T cells reveals vaccination-induced dominant Tfh clonotypes, not pre-existing T cells, associated with sustained humoral response, and can serve as an index of antigen-specific antibody longevity.
    1. Genetics and Genomics
    2. Immunology and Inflammation

    Sustained store-operated calcium entry utilizing activated chromatin state leads to instability in iTregs

    Huiyun Lyu, Guohua Yuan ... Yan Shi
    Multidimensional study of signaling pathways and epigenomics investigates how TCR (T cell receptor) signaling and chromatin landscape interpaly and impact on Treg stability.
    1. Immunology and Inflammation

    MARCO in alveolar macrophages negatively regulates Ace expression and aldosterone production

    Conan J O O’Brien, Giorgio Ratti ... Ana I Domingos
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Neuroscience

    Optogenetic Stimulation of Single Ganglion Cells in the Living Primate Fovea

    Peter J. Murphy, Juliette E. McGregor ... David R. Williams
    Not revised
    Reviewed Preprint v1
    • Important
    • Incomplete
    1. Microbiology and Infectious Disease

    Cell detoxification of secondary metabolites by P4-ATPase-mediated vesicle transport

    Yujie Li, Hui Ren ... Yan Pei
    P4-ATPase BbCrpa detoxifies secondary metabolites via a unique vesicle-mediated transport pathway that targets the compounds into vacuoles.
    1. Immunology and Inflammation

    ARPC5 isoforms and their regulation by calcium-calmodulin-N-WASP drive distinct Arp2/3-dependent actin remodeling events in CD4 T cells

    Lopamudra Sadhu, Nikolaos Tsopoulidis ... Oliver T Fackler
    Selective involvement of Arp2/3 complex subunit isoforms ARPC5 or ARPC5L governs the distinct actin polymerization events in the nucleus or cytoplasm of CD4 T cells that are triggerd by T cell activation or DNA replication stress.
Load more

Refine your results by:

Type
Research categories