Lineage tracing using a knockin Pdgfra-rtTA tool indicates distinct contributions of this cell lineage to myofibroblasts in normal development, fibrosis and bronchopulmonary dysplasia models.

Regulation of cellular properties such as ligand secretion and migratory ability through changes in the cytoskeleton mediated by a Wnt5a–Ror2–Vangl2 axis is a major determinant of alveolar formation.

Stromal cell levels and localization of active α₅β₁-integrin are regulated by desmoplastic extracellular matrix control of α_vβ₅-integrin signaling, and predict clinical outcomes for pancreatic and renal cancer patients.

Engagement of both host and parasite signaling pathways proves a novel approach for developing improved anti-parasitic therapies.

Lactate in pancreatic cancer micro-environment can lead to TET enzyme activation and loss of DNA methylation seen in cancer associated fibroblasts.

Editors' Summary: This Replication Study has reproduced important parts of the original paper.

The combination of ceritinib with CGM097 demonstrates remarkable antitumor activity in TP53 wild-type neuroblastoma models with ALK aberrations and is able to overcome the resistance acquired during ceritinib treatment.

Inflammatory cells differentially regulate a scarring versus a regenerating response to injury in mammals.

Neural crest cells differentiated from patient-derived cells with mutations in the chromatin remodeler CHD7 show defective delamination, migration and motility in vitro, and defective migration in chick embryos.

Modelling beta-amyloid deposition in bioengineered human vessels represents a notable advance to further investigate the role of the vasculature in Alzheimer's disease.