Analysing Myosin II unipolar planar polarisation with high spatial and temporal resolution during Drosophila axis extension reveals how tissue boundaries drive polarized cell intercalation while limiting cell mixing.
Vibrator and PI4KIIIα that stimulate the synthesis of PI(4)P anchor non-muscle myosin II RLC (Sqh) to the plasma membrane and conversely Sqh associates with PI(4)P and facilitates its membrane localization during asymmetric division of neuroblasts.
Positive feedback between contractile ring myosin and compression-driven cortical flow can explain the exponential accumulation of contractile ring components and constriction rate acceleration that ensures timely cell separation during cytokinesis.
A lipid mediator lysophosphatidic acid (LPA) derived from fibroblastic reticular cells regulates T-cell movement through the densely packed reticular network in lymph nodes in a manner dependent on the LPA receptor LPA2-ROCK-myosin II.
Publication bias, in which positive results are preferentially reported by authors and published by journals, can restrict the visibility of evidence against false claims and allow such claims to be canonized inappropriately as facts.