Combined Inhibition of DNA replication and repair synergistically prevents tumor growth, representing a promising strategy for cancer therapy.

Differentiation of the pathogenic bacterium, Chlamydia trachomatis, from its non-infectious to infectious form is linked to the redox state of the organism.

A new example of niche formation, revealing the mode of niche cell migration, implicates extrinsic sources of positional information, and uncovers the pathway required for stereotypical positioning of the niche.

Analysis of genome-wide spatial transcriptomics data reveals cell-type specific subcellular RNA localization, and a subset of genes show significantly high correlation between spatial patterning and 3' UTR length.

Titin’s regulated integration and mobility after cell fusion support syncytium formation in culture, while limited diffusion in vivo highlights a key challenge for developing effective cell-based therapies for skeletal muscle diseases.