Tn5 transposase has direct tagmentation activity towards RNA/DNA hybrids, which is harnessed as a more convenient and faster RNA-seq library construction method and will benefit RNA and chromatin research.
Cellularization in Sphaeroforma arctica generates a self-organized structure that morphologically resembles an epithelium, and is associated with tightly regulated expression of cell adhesion pathways.
Humans showed the most widespread asymmetric connectivity between the inferior parietal lobule subregions and the rest of the brain compared to macaques and chimpanzees, which shapes hemispheric specialization in primates.
Prenylation of human oligoadenylate synthetase 1 isoform p46 mediates endomembrane targeting and increases its antiviral activity against positive-strand RNA viruses that utilize the host endomembrane system for replication.
Patterned optogenetic stimulation and analysis of neural activity provide convergent evidence that cerebellar Purkinje cells drive eye movements with a rapid rate code, without an additional contribution of spike irregularity.