A combination of molecular dynamics simulations and X-ray diffraction data has been used to construct more realistic models of proteins and to provide new insights into their interactions with other proteins and biomolecules.

A cellular motor protein helps to ensure that microtubules are oriented correctly within neuronal dendrites

Computer simulations reveal that viral nucleic acids have an ideal structure for being packaged into outer protein shells called capsids.

Cryo-electron tomography reveals how a chaperone protein called TRiC reduces the ability of pathogenic mutant huntingtin proteins to form aggregates.

The proteins Bax and Bak, which increase the permeability of the mitochondrial membrane during apoptosis, are also crucial for generating a mitochondrial membrane pore that is specifically involved in necrosis.

Tracking individual mice within a group makes it possible to quantify and model social behavior, and reveals that the behavior of the group goes beyond pairwise interactions, and is shaped by complex interactions between multiple individuals.

High-resolution optical microscopy is used to reveal the organization of extracellular matrix proteins within the basement membrane of the blood filtration barrier in the kidney at the nanometer scale.