705 results found
  1. Episode 44: January 2018

    In this episode, we hear about self-esteem, a new genus of extinct horse, the future of biological engineering, mosquito trackers, and sperm competition in salmon.
  2. February 2014

    Episode 9: February 2014

    In this episode we learn more about sleep, super Spy chaperones, swimming bacteria, orphan genes and the neuroscience of birdsong.
    1. Structural Biology and Molecular Biophysics

    Three dimensional reconstruction of energy stores for jumping in planthoppers and froghoppers from confocal laser scanning microscopy

    Igor Siwanowicz, Malcolm Burrows
    Three dimensional reconstructions of the mechanical energy stores of jumping insects reveal how the miniaturized components interact and function.
    1. Cell Biology
    2. Plant Biology

    Fluorescent sensors reporting the activity of ammonium transceptors in live cells

    Roberto De Michele et al.
    A modified form of Green Fluorescent Protein integrated into an ammonium transporter provides a sensor that can be used to monitor transport activity in vivo.
    1. Immunology and Inflammation

    Functionally diverse human T cells recognize non-microbial antigens presented by MR1

    Marco Lepore et al.
    MR1T cells are human polyclonal T cells endowed with diverse effector functions in response to endogenous antigens presented by MHC-class 1-related molecule, MR1.
    1. Cell Biology
    2. Neuroscience

    Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells

    Matthew J Sternfeld et al.
    Stem cell derived ventral-spinal cord excitatory neurons self-assemble into a rhythmically bursting neural network whose speed and intercellular coordination are both instructively modulated by cell-type specific interactions with inhibitory neurons.
    1. Cancer Biology
    2. Cell Biology

    One reporter for in-cell activity profiling of majority of protein kinase oncogenes

    Iva Gudernova et al.
    A new luciferase and fluorescent reporter system enables rapid and efficient in-cell profiling of the majority of protein kinase oncogenes known to date.
    1. Biochemistry and Chemical Biology
    2. Structural Biology and Molecular Biophysics

    Eukaryotic translation initiation factor 3 plays distinct roles at the mRNA entry and exit channels of the ribosomal preinitiation complex

    Colin Echeverría Aitken et al.
    Eukaryotic translation initiation factor 3 (eIF3) is required to stabilize the binding of mRNA at the exit channel of the small ribosomal subunit and acts at the entry channel to accelerate mRNA recruitment to the translation preinitiation complex.
    1. Computational and Systems Biology
    2. Neuroscience

    Resolving coiled shapes reveals new reorientation behaviors in C. elegans

    Onno D Broekmans et al.
    A conceptually simple algorithm can analyze previously uncharacterized 2D coiled postures of the nematode C. elegans and has uncovered new reorientation behaviors in large amplitude turns.
    1. Biochemistry and Chemical Biology
    2. Cell Biology

    The Lamin B receptor is essential for cholesterol synthesis and perturbed by disease-causing mutations

    Pei-Ling Tsai et al.
    Lamin B receptor may provide a long-sought model system enabling unprecedented studies of protein quality control in the nuclear envelope of mammalian cells.

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