The lysine acetyltransferases KAT2A and KAT2B regulate the dynamic chromatin association of the tumour suppressor protein PALB2, protecting active genes and promoting DNA damage repair in a context-dependent manner.

Osteoblast dedifferentiation and migration are injury responses that are differentially regulated and independent of regenerative bone formation.

Investigation of the role of triple-stranded nucleic acid, R-loops, in HIV-1 genome integration.

B cells regulate production of neutrophils by a novel mechanism by releasing ST6Gal-1, an active sialyltransferase, that suppresses granulopoiesis.

Multiple biochemical assays show that the topology of CCR5 and possibly other GPCRs may be inverted by ceramide or other sphingolipids through the process of regulated alternative translocation.

The number of CENP-A molecules at human centromeres helps to explain how this structure is built and epigenetically inherited.

Structural biology studies reveal the importance of protein dynamics on understanding molecular mechanisms underlying allosteric modulation of G protein-coupled receptors (GPCR) that offer insights into future GPCR research and drug discovery.

mRNA decay contributes to reshape the transcriptome as a parent cell divides into daughter cells.

Prokaryotes use polycistronic messages for coordinated translation, whereas eukaryotic cells may achieve tunable protein synthesis by packaging monocistronic mRNAs into functional multiplexes via co-transcriptional interallelic coupling and non-canonical histone-H4 functions.

The efficient deployment of RdDM for transposon silencing is hierarchically controlled by the linker histone H1.