Michael Garratt, Ilkim Erturk ... Richard A Miller
Early-life exposure to conspecific urine and bedding extends the lifespan of female mice, indicating that social chemosensory cues can influence aging in a mammal.
David M Garcia, Edgar A Campbell ... Daniel F Jarosz
In its capacity to switch into a heritable, prionogenic form, a conserved RNA-modifying enzyme epigenetically alters fundamental growth, aging, and protein synthesis properties of eukaryotic cells.
Natural temperature variation across an optimal reproductive range for wild flies (Drosophila melanogaster) modulates the impact of sexual conflict on female fitness via asymmetric effects on pre- and post-copulatory male harm mechanisms.
Laure Mignerot, Clotilde Gimond ... Christian Braendle
Caenorhabditis elegans egg-laying behaviour shows pronounced variation in natural populations, making it a promising model to investigate the microevolution of a simple neural circuit.
Mirela Zaneva, Tao Coll-Martín ... Alyssa Hillary Zisk
A collaboratively developed annotated reading list expands upon core themes in neurodiversity, aiming to enhance understanding and to promote rigorous, destigmatizing, and inclusive practices in research.
By controlling the SUMOylation of the protein CAR-1, the aging-regulating pathways downstream of the Insulin/IGF signaling cascade and of the germ cells of the nematode Caenorhabditis elegans are integrated.
As worms age reduced glutathione together with increased ferrous iron increases frailty and leads to ferroptosis, which is amenable to therapeutic intervention.
A powerful sequencing approach is used to elucidate the genetic basis of a complex organismal trait, and members of the irld gene family that affect starvation resistance are identified.
Daniel W Belsky, Avshalom Caspi ... Terrie E Moffitt
Methylation pace of aging is a novel measure requiring only a blood sample that clinical-trial and observational studies can use to test if treatments modify how fast participants are aging.