The lysosomal ion channel TPC2 emerges as an example of an ion channel in which ion selectivity is not fixed but rather agonist-selective.

Lymphocytes and monocytes maintain their cell surface HLA-B via different mechanisms, which in turn differently influence cell-surface expression, half-life and peptide receptivity of HLA-B allotypes.

The synaptic ribbon regulates calcium channel clustering and proper vesicle dynamics at cochlear inner hair cells to ensure precise sound encoding.

Allosteric mechanism of dual β-lactam binding in L,D-transpeptidase from Mycobacterium tuberculosis.

Post-translational regulation of retrotransposons plays a key role in preventing retrotransposon mobilization in the epigenetically dynamic mouse germline.

The pattern of spatial attention preferences in caudate neurons is altered by superior colliculus inactivation, demonstrating that a superior colliculus to basal ganglia link is important for selective attention.

Deletion of Arginase 1 in myeloid cells delays tumor formation in pancreatic cancer.

The higher order thalamus encodes and influences correct action during learning and performance in a sensory-based goal-directed behavior.

Elevated growth differentiation factor-15 (GDF15) levels do not appear to be a causal factor in body mass index (BMI) in humans but higher BMI does cause increases in GDF15.

In the injured sciatic nerve, blood-derived monocytes and macrophages eat dying leukocytes, thereby contributing to nerve debridement and inflammation resolution, and this correlates with neuronal regeneration.