CPT1A downregulation enhances radioresistance in colorectal cancer (CRC) via FOXM1-mediated antioxidant response, making it a potential biomarker for radiosensitivity and a novel target for improving CRC radiotherapy.

Post-transcriptional regulation of Aurora Kinase A (AURKA) through alternative polyadenylation of its mRNA determines miRNA influence and is a feature of cell cycle-specific AURKA expression whose impairment leads to acquisition of cancer phenotypes.

Exploring how UBQLN2 mutations cause ALS leads to the discovery of a pathway by which an ancient retroelement changes gene expression in human cells.

Mettl3 post-transcriptionally reduces Fgf16 mRNA levels through an m⁶A-Ythdf2-dependen pathway, thereby controlling cardiomyocyte proliferation and heart regeneration.

Characterization of Ca²⁺ selectivity and non-conductance mechanism induced by pore mutation N617D in the skeletal muscle DHPR.

Transient weakness in myotonia congenita is caused by depolarization secondary to activation of persistent Na⁺ current in skeletal muscle.

Ultrastructural and loss-of-function experiments show that oligodendrocyte-encoded Kir4.1 is located near active axonal structures, including within myelin inner tongue, and has critical functions to promote axonal activity and preserve integrity.

Development of a generally adaptable conformational capture assay for use in-trans identifies the specific direct interaction sites between the parvovirus minute virus of mice and the cellular genome during infection as sites of cellular DNA damage.

A novel component of type III protein secretion systems involved in the assembly of the secretion machine is reported.