Vocal development in marmoset monkeys begins in utero.

The neonatally maturing pituitary harbors an activated stem cell compartment and shows prominent regenerative capacity, as revealed by single-cell transcriptomic profiling and in vitro (organoid) and in vivo (mouse) exploration.

Mutations causing proinsulin misfolding trigger unfolded protein response and lead to impaired proliferation and reduced mTORC1 signalling of developing beta-cells in a patient-derived induced pluripotent stem cell disease model.

Normalizing Tcf4 expression during early postnatal development improves behavioral outcomes in Pitt-Hopkins syndrome (PTHS) model mice, suggesting that genetic therapies are feasible in individuals with PTHS.

The structural and functional development of human infant visual cortex can be modulated by the external environment.

At the transition from intrauterine to postnatal life, drastic environmental alterations are mirrored by changes in cellular immunity, which are in part immune cell intrinsic and have lasting health impact.

A single-nucleus transcriptomic atlas reveals the molecular signatures and trajectory dynamics of the neurogenic lineage in the human hippocampus during neonatal development, adulthood, aging, and after injury.

β2-adrenergic receptors control glucose metabolism by regulating cross-talk between pancreatic islet endocrine cells and vasculature during development.

Age-specific transcriptional responses to Flt3-ITD and cooperating Flt3/Runx1 mutations cause hematopoietic stem cell depletion and myeloid progenitor expansion during adult, but not fetal/neonatal, stages of development.

Functional and anatomical analysis reveal a crucial role played during embryonic development by microglia in the ontogenesis and function of central circuits responsible for respiratory rhythmogenesis.