1,496 results found
    1. Developmental Biology

    Branching morphogenesis in the developing kidney is not impacted by nephron formation or integration

    Kieran M Short et al.
    Analysing developing mouse kidneys demonstrates nephron formation does not significantly impact branching morphogenesis of the ureteric bud, suggesting this process is distinct from branching in organs like the mammary gland.
    1. Cell Biology
    2. Neuroscience

    Aberrant information transfer interferes with functional axon regeneration

    Chen Ding, Marc Hammarlund
    Defects in synapse regeneration limit functional circuit recovery after nerve injury by misdirecting information via ectopic dendritic synapses, and also by functional and molecular deficits in reformed axonal synapses.
    1. Neuroscience

    Generalizable knowledge outweighs incidental details in prefrontal ensemble code over time

    Mark D Morrissey et al.
    Neuron ensembles in the medial prefrontal cortex gradually develop codes for relevant, latent variables common across multiple experiences while – apparently independently – losing information about irrelevant, contextual variables unique to each experience.
    1. Developmental Biology
    2. Neuroscience

    Regulation of subcellular dendritic synapse specificity by axon guidance cues

    Emily C Sales et al.
    Axon guidance cues restrict sensory neuron synapse formation to a subset of equally acceptable interneuronal dendritic arbors during Drosophila locomotor circuit assembly.
    1. Neuroscience

    Multiple conserved cell adhesion protein interactions mediate neural wiring of a sensory circuit in C. elegans

    Byunghyuk Kim, Scott W Emmons
    The formation of neuronal connectivity of a C. elegans neuron pair is promoted by multiplexed interactions of neural cell adhesion proteins, which are evolutionarily conserved across animal taxa.
    1. Cell Biology

    Akt1-Inhibitor of DNA binding2 is essential for growth cone formation and axon growth and promotes central nervous system axon regeneration

    Hyo Rim Ko et al.
    Akt mediated S14 phosphorylation of Id2 augments its protein stability and growth cone localization, promoting growth cone formation and axon growth in the developing neuron and contributing to axon regeneration in the damaged hippocampus slice.
    1. Developmental Biology
    2. Neuroscience

    Stereotyped terminal axon branching of leg motor neurons mediated by IgSF proteins DIP-α and Dpr10

    Lalanti Venkatasubramanian et al.
    Ig domain family members DIP-alpha and Dpr10 are required in a subset of Drosophila leg motor neurons and muscles, respectively, to establish their fine terminal branching pattern and synapses.
    1. Neuroscience

    Neuroplasticity: Exciting experiences make neurons less excitable

    Prakruti Nanda et al.
    Neurons in the brain of a female mouse that respond to the scent of a given male become suppressed after mating.
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    1. Neuroscience

    Axons: The cost of communication in the brain

    Brian A MacVicar et al.
    Imaging ATP in axons reveals that they rely on glucose from the blood and lactate produced by glial cells as sources of energy.
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    1. Cell Biology
    2. Developmental Biology

    Genetic Screen: Hearing lessons from flies

    Yi-Nan Lee, Cheng-Ting Chien
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