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Page 3 of 158
    1. Developmental Biology
    2. Neuroscience

    Transcriptional profiling of mouse peripheral nerves to the single-cell level to build a sciatic nerve ATlas (SNAT)

    Daniel Gerber, Jorge A Pereira ... Ueli Suter
    Establishing transcriptional profiles of nerve-inhabitant cells as resource to foster the fundamental understanding of peripheral nerves.
    1. Developmental Biology
    2. Neuroscience

    MEGF8 is a modifier of BMP signaling in trigeminal sensory neurons

    Caitlin Engelhard, Sarah Sarsfield ... David D Ginty
    A protein called Megf8 regulates the activity of key signaling molecules involved in the development of the peripheral nervous system.
    1. Developmental Biology
    2. Neuroscience

    Sequential addition of neuronal stem cell temporal cohorts generates a feed-forward circuit in the Drosophila larval nerve cord

    Yi-wen Wang, Chris C Wreden ... Ellie Heckscher
    A newly identified pattern of circuit assembly shows connectivity between small groups of neurons born in tight time windows from different stem cells, with outputs from one lineage born before inputs from other lineages.
    1. Developmental Biology

    Taste bud formation depends on taste nerves

    Di Fan, Zoubida Chettouh ... Jean-François Brunet
    The sensory nerves that carry sensations from the taste buds to the brain induce the formation of the taste buds in the embryo.
    1. Developmental Biology
    2. Neuroscience

    Anterior CNS expansion driven by brain transcription factors

    Jesús Rodriguez Curt, Behzad Yaghmaeian Salmani, Stefan Thor
    The expansion of the anterior Drosophila CNS is driven by increased progenitor generation and prolonged proliferation, mediated by brain-restricted genes and the PRC2.
    1. Stem Cells and Regenerative Medicine

    An optogenetic cell therapy to restore control of target muscles in an aggressive mouse model of amyotrophic lateral sclerosis

    J Barney Bryson, Alexandra Kourgiantaki ... Linda Greensmith
    Stem-cell-based neural replacement, in combination with optogenetic stimulation, could represent a translationally viable therapeutic strategy to overcome atrophy and paralysis of targeted muscles in people living with amyotrophic lateral sclerosis.
    1. Immunology and Inflammation

    Neuron-associated macrophage proliferation in the sensory ganglia is associated with peripheral nerve injury-induced neuropathic pain involving CX3CR1 signaling

    Rafaela M Guimarães, Conceição E Aníbal-Silva ... Thiago M Cunha
    CX3CR1-signaling in sensory ganglia macrophages mediates their proliferation/activation, as well as the production of pro-inflammatory mediators that contribute to neuropathic pain.
    1. Neuroscience

    Dual leucine zipper kinase is required for mechanical allodynia and microgliosis after nerve injury

    Josette J Wlaschin, Jacob M Gluski ... Claire E Le Pichon
    The DLK response pathway in neurons initiates the cascade of events leading to neuropathic pain after injury.
    1. Neuroscience

    Embryonic and postnatal neurogenesis produce functionally distinct subclasses of dopaminergic neuron

    Elisa Galliano, Eleonora Franzoni ... Matthew S Grubb
    In the mouse olfactory bulb, different types of local dopaminergic interneuron are produced before and after birth.
    1. Neuroscience

    Stereotyped transcriptomic transformation of somatosensory neurons in response to injury

    Minh Q Nguyen, Claire E Le Pichon, Nicholas Ryba
    Peripheral injury induces a programmed but reversible transformation of gene expression in somatosensory neurons providing a mechanism to regulate sensory input during wound healing.