3,112 results found
  1. Cutting Edge: A network approach to mixing delegates at meetings

    Federico Vaggi et al.
    A network-based ‘speed dating’ approach can promote interactions between delegates at scientific meetings.
    1. Computational and Systems Biology
    2. Neuroscience

    Learning: Neural networks subtract and conquer

    Guillaume Hennequin
    Two theoretical studies reveal how networks of neurons may behave during reward-based learning.
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    1. Cell Biology

    The Mitotic Exit Network integrates temporal and spatial signals by distributing regulation across multiple components

    Ian Winsten Campbell et al.
    By distributing regulation to both the GTPase and downstream kinases, the Mitotic Exit Network creates a single signal from spatial and temporal inputs.
    1. Neuroscience

    Functionally defined white matter of the macaque monkey brain reveals a dorso-ventral attention network

    Ilaria Sani et al.
    Primate attention is not limited to a dorsal fronto-parietal network, but includes a ventral temporal node and its dorso-ventral interactions with other attentional areas.
    1. Neuroscience

    Inhibitory control of correlated intrinsic variability in cortical networks

    Carsen Stringer et al.
    A new cortical network model fit directly to multi-neuron recordings reveals that local inhibitory feedback can control neural dynamics, modulate brain state and enhance sensory processing.
    1. Biochemistry and Chemical Biology

    Prediction and characterization of enzymatic activities guided by sequence similarity and genome neighborhood networks

    Suwen Zhao et al.
    Genome neighborhood networks provide an efficient large-scale approach to mine metabolic pathway context for entire families of proteins and enzymes.
    1. Computational and Systems Biology
    2. Neuroscience

    Fast and flexible sequence induction in spiking neural networks via rapid excitability changes

    Rich Pang, Adrienne L Fairhall
    Biologically plausible changes in the excitabilities of single neurons may suffice to selectively modulate sequential network dynamics, without modifying of recurrent connectivity.
    1. Chromosomes and Gene Expression
    2. Evolutionary Biology

    Cis-regulatory evolution integrated the Bric-à-brac transcription factors into a novel fruit fly gene regulatory network

    Maxwell J Roeske et al.
    The conserved biochemical activity of the duplicate Bab transcription factors were integrated into the regulatory hierarchy of an evolving gene regulatory network by binding site gains in a target gene's cis-regulatory region.
    1. Computational and Systems Biology
    2. Neuroscience

    Biologically plausible learning in recurrent neural networks reproduces neural dynamics observed during cognitive tasks

    Thomas Miconi
    A biologically plausible learning rule allows recurrent neural networks to learn nontrivial tasks, using only sparse, delayed rewards, and the neural dynamics of trained networks exhibit complex dynamics observed in animal frontal cortices.
    1. Computational and Systems Biology

    Engineering of a synthetic quadrastable gene network to approach Waddington landscape and cell fate determination

    Fuqing Wu et al.
    A synthetic quadrastable gene network provides a synthetic biology framework to study cell fate determination.

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