Cortical network model suggests a mechanism explaining the link between NMDAR synaptic and spike synchrony deficits observed in a pharmacological monkey model of prefrontal network failure in schizophrenia.
Godber M Godbersen, Sebastian Klug ... Andreas Hahn
In the human brain, default mode network BOLD deactivations can be accompanied by both increases and decreases in glucose metabolism, depending on the respective metabolic demands of task-positive cognitive control and attention networks.
The learning rate for novel spatial environments in model networks of place cells is determined by the product of the window for plasticity and the auto-correlation of place-cell activity.
Recurrent neural networks trained to navigate and infer latent states exhibit strikingly similar remapping patterns to those observed in navigational brain areas, inspiring new analyses of published data and suggesting a possible function for spontaneous remapping to support context-dependent navigation.
The default mode network in the brain is activated during the performance of executive-type tasks when a substantial change in cognitive contents is required.
A neural network model of the hippocampus exhibits a division of labor across its two main pathways during category learning, with one pathway specializing in extracting systematic category information and another in encoding arbitrary details.
Unprecedented 4D spatiotemporal infant regional cerebral blood flow framework and region-specific physiology–function coupling across infancy were elucidated, highlighting strong physiology–function coupling specifically at the default-mode network to meet extraneuronal metabolic demand for network emergence.
Simple modifications to early stages of the visual hierarchy, such as gain changes, can induce complex effects on later stages, but only gain is both necessary and sufficient to explain enhanced perception during spatial attention.
Spontaneous theta oscillations and interneuron-specific phase preferences emerge spontaneously in a full-scale model of the isolated hippocampal CA1 subfield, corroborating and extending recent experimental findings.
Functional hypoconnectivity between ‘social brain’ default mode circuitry and visual association cortex underpins a subtype of autistic toddlers with a strong preference to attend to the non-social visual world.
