4,387 results found
    1. Medicine
    2. Neuroscience

    The effect of transcutaneous auricular vagus nerve stimulation on cardiovascular function in subarachnoid hemorrhage patients: A randomized trial

    Gansheng Tan, Anna L Huguenard ... Eric C Leuthardt
    Transcutaneous auricular vagus nerve stimulation is a safe neuromodulatory treatment for subarachnoid hemorrhage patients, with potential benefits for restoring autonomic balance.
    1. Ecology

    The cuticular hydrocarbon profiles of honey bee workers develop via a socially-modulated innate process

    Cassondra L Vernier, Joshua J Krupp ... Yehuda Ben-Shahar
    Chemical nestmate recognition in honey bee colonies depends on an innate, socially modulated developmental process.
    1. Neuroscience

    Septal cholinergic input to CA2 hippocampal region controls social novelty discrimination via nicotinic receptor-mediated disinhibition

    Domenico Pimpinella, Valentina Mastrorilli ... Marilena Griguoli
    Acetylcholine, released from cholinergic fibers originating from the medial septum, shapes social memory, and controls the CA2 hippocampal circuit via nicotinic receptors localized on GABAergic interneurons.
    1. Neuroscience

    Cellular and neurochemical basis of sleep stages in the thalamocortical network

    Giri P Krishnan, Sylvain Chauvette ... Maxim Bazhenov
    A computational model of the thalamocortical network explains sleep stages by the coordinated variations in the level of neuromodulators and predicts differences of sleep pattern in human, cat and mouse recordings.
    1. Cell Biology
    2. Neuroscience

    Synaptotagmin 7 docks synaptic vesicles to support facilitation and Doc2α-triggered asynchronous release

    Zhenyong Wu, Grant F Kusick ... Shigeki Watanabe
    The calcium-binding proteins synaptotagmin 7 and Doc2α act sequentially during asynchronous neurotransmitter release.
    1. Neuroscience

    The effects of chloride dynamics on substantia nigra pars reticulata responses to pallidal and striatal inputs

    Ryan S Phillips, Ian Rosner ... Jonathan E Rubin
    The effects of chloride homeostasis can explain diverse responses of basal ganglia output neurons to putatively inhibitory inputs and may tune these neurons' synchrony, oscillations and behavior in decision-making scenarios.
    1. Neuroscience

    Impaired astrocytic Ca2+ signaling in awake-behaving Alzheimer’s disease transgenic mice

    Knut Sindre Åbjørsbråten, Gry HE Syverstad Skaaraas ... Rune Enger
    Noradrenaline-mediated astrocytic Ca2+ signaling in behavior is reduced in awake-behaving tg-ArcSwe Alzheimer's disease transgenic mice.
    1. Cell Biology
    2. Genetics and Genomics

    A mitochondrial DNA hypomorph of cytochrome oxidase specifically impairs male fertility in Drosophila melanogaster

    Maulik R Patel, Ganesh K Miriyala ... Harmit S Malik
    A 'male-harming' mtDNA mutation has been identified in Drosophila and impairs male fertility without impairing other male or female functions.
    1. Immunology and Inflammation

    Selective loss of CD107a TIGIT+ memory HIV-1-specific CD8+ T cells in PLWH over a decade of ART

    Oscar Blanch-Lombarte, Dan Ouchi ... Julia G Prado
    PLWH over a decade of ART showed a significant reshaping of the function and expression of inhibitory receptors across the CD8+ T cell landscape, ultimately leading to a decrease of CD107a TIGIT HIV-1-specific CD8+ T cells recovered by TIGIT blockade.
    1. Neuroscience

    Huntingtin recruits KIF1A to transport synaptic vesicle precursors along the mouse axon to support synaptic transmission and motor skill learning

    Hélène Vitet, Julie Bruyère ... Frédéric Saudou
    Studies in mice and neurons reveal how modulation of the axonal transport of synaptic vesicles via huntingtin phosphorylation influences the number of vesicles accumulating at the synapse, subsequent glutamate release, and behavior in mice.

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