Neurophysiological and behavioral approaches reveal how coordinated input from descending pathways shapes the tuning properties of electrosensory neurons in order to optimize coding of natural stimuli through temporal whitening.
Whether central vestibular neurons implement faithful stimulus encoding for the vestibulo-occular reflex or optimized coding via temporal whitening for other vestibular functions is determined by neural variability.
Building on previous work (Metzen et al., 2016), a combination of neurophysiological and behavioral approaches reveals that changes in the background strongly impacts invariant coding and perception of behaviourally relevant signals.
Neuronal ELAV-like (nELAVL) proteins are associated with non-coding Y RNAs in stressed neurons and in the brains of Alzheimer's disease patients, suggesting a new means of regulatory protein sequestration and mRNA target regulation.
The novel neural marker for the integration of top-down predictions and bottom-up signals in perception elucidates uncertainty in perceptual inference and provides evidence for the predictive coding account of perception.