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    1. Developmental Biology
    2. Neuroscience

    Pioneer neurog1 expressing cells ingress into the otic epithelium and instruct neuronal specification

    Esteban Hoijman et al.
    Quantitative 4D image analysis identifies a group of cells which enter into the otic primordium during morphogenesis and instructs neuronal specification.
    1. Developmental Biology
    2. Neuroscience

    Spinal cord precursors utilize neural crest cell mechanisms to generate hybrid peripheral myelinating glia

    Laura Fontenas, Sarah Kucenas
    Motor exit point (MEP) glia utilize mechanisms most commonly attributed to neural crest cells for their development from spinal cord precursors.
    1. Structural Biology and Molecular Biophysics

    Structures of two aptamers with differing ligand specificity reveal ruggedness in the functional landscape of RNA

    Andrew John Knappenberger et al.
    RNA aptamers that are closely related and share a common scaffold can readily adapt to recognize new ligands through changes in just a few nucleotides.
    1. Developmental Biology

    Distinct mesoderm migration phenotypes in extra-embryonic and embryonic regions of the early mouse embryo

    Bechara Saykali et al.
    At gastrulation, mesoderm arises as a migratory germ layer that will participate to both foetal and placental development through region-dependant adaptation of cytoskeleton composition, cell shape and migration mode.
    1. Developmental Biology

    Cardiac neural crest contributes to cardiomyocytes in amniotes and heart regeneration in zebrafish

    Weiyi Tang et al.
    Lineage analysis reveals that cardiac neural crest contributes to cardiomyocytes across vertebrates and consistent with this, the neural crest gene regulatory program is reactivated upon heart regeneration in zebrafish.
    1. Cell Biology
    2. Developmental Biology

    TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation

    Xiaochen Fan et al.
    Network propagation connects TWIST1 with epigenetic regulators CHD7, CHD8, and WHSC1, which collectively promote the bias toward neural crest while suppressing neural stem cell programmes, and subsequently enhance ectomesenchyme potential.
    1. Developmental Biology

    Evolution of the hypoxia-sensitive cells involved in amniote respiratory reflexes

    Dorit Hockman et al.
    Embryonic fate-mapping approaches in zebrafish, Xenopus and lamprey illuminate the evolutionary origins of carotid body glomus cells and pulmonary neuroendocrine cells.
    1. Developmental Biology
    2. Evolutionary Biology

    Bichir external gills arise via heterochronic shift that accelerates hyoid arch development

    Jan Stundl et al.
    Unique heterochrony in the cranial segments in bichirs triggers the early formation of their external gills, and might be informative about developmental mechanisms facilitating increased breathing capacity.
    1. Developmental Biology

    Dynamic transcriptional signature and cell fate analysis reveals plasticity of individual neural plate border cells

    Daniela Roellig et al.
    The vertebrate neural plate border is comprised of precursors that coexpress multiple lineage markers and small changes in their levels can bias border cell fate.