Anchoring of proteins to the cell membrane through the glycosylphosphatidylinositol (GPI) anchor is critical for the survival of the cells that will give rise to the brain and face.

Neural progenitors in humans and chimpanzee organoids show remarkably similar cellular and molecular parameters, but metaphase is longer during human mitosis.

A comparative approach shows that developmental evolution of neuropeptidergic neuronal groups in the hypothalamus of blind cavefish drives adaptive behavioral evolution.

Mouse in vivo and in vitro analysis and human genetic screening highlight the role of anti-Müllerian hormone (AMH) signaling in GnRH neuronal development and function, and identify mutations in AMH and AMHR2 in CHH patients.

mTORC1 and mTORC2 play a central role in the development of natural killer (NK) cells.

Signaling from glia and nerves regulate the development of axonal and dendritic motor neuron architecture, needed for walking in the fruit fly species Drosophila.

Glycolysis is locally enhanced and redirected in zebrafish to generate lactate, which functions as a signaling molecule to fully activate Fgf target genes required for proper sensory and neural development.

Neural retina-derived retinoic acids synthesized by Aldh1a1 control choroidal vascular development by regulating RPE-secreted VEGF.

PTBP2 ensures that adult protein variants are expressed only in mature neurons through regulation of alternative splicing during early neuronal development.

Single-cell transcriptomics combined with genetic analyses identify post-embryonic neural crest subpopulations and thyroid hormone dependencies in zebrafish adult pigment pattern development.