Sequentially expressed temporal transcription factors in neural stem cells during early development determine which progeny can undergo malignant transformation upon dedifferentiation.

Neural progenitors in humans and chimpanzee organoids show remarkably similar cellular and molecular parameters, but metaphase is longer during human mitosis.

NEIL DNA glycosylases are required to counteract oxidative base damages within the mitochondrial genome to safeguard neural crest cell differentiation.

Neural retina-derived retinoic acids synthesized by Aldh1a1 control choroidal vascular development by regulating RPE-secreted VEGF.

A model of in vitro human corticogenesis identifies alterations in gene expression caused by loss of 16p11.2 CNV genes in hiPSC-derived progenitor cells.

Akt activation is required for neural crest differentiation through regulation of Sox10 activity.

Alternative splicing of the Dcc gene, which is controlled by the NOVA RNA-binding proteins, is crucial during neuronal migration and axon guidance.

Timing in the formation of neurons influences synaptic connectivity.

A novel, translational mouse model of prenatal methadone exposure was developed and a longitudinal assessment of offspring revealed impairments in physical, behavioral, and neuronal development.

The RNA-binding protein NOVA2 coordinately regulates the alternative splicing of key components in axon guidance and outgrowth pathways, with severe functional consequences.