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The combination of data and modelling shows the mechanisms underlying bidirectional flow of cerebrospinal fluid and its impact on long range transport in the CSF between brain and spinal cord.

The DIAMonDS can automatically and sequentially identify time points of multiple life cycle events such as pupariation, eclosion, and death in individual flies at high temporal resolution and large scale.

Cartilage cells transition through a proliferative intermediate to give rise to bone and marrow fat cells in long bones.

Both gill musculature and the evolutionarily conserved cucullaris muscle are derived from unsegmented mesoderm adjacent to the first 3 somites, extending the posterior limit of cranial mesoderm.

Vertebrate early ectoderm displays planar polarity manifested by a fluorescent sensor and this polarity can be instructed by Wnt ligands.

Skeletal muscle organoids differentiated from human pluripotent stem cells offer a system for investigating myogenesis and satellite cell development with translational potential for muscular dystrophy modeling and therapy development.

Xenopus embryos use tissue surface tension to generate hoop-stress around the blastopore to help close it during gastrulation.

NEIL DNA glycosylases are required to counteract oxidative base damages within the mitochondrial genome to safeguard neural crest cell differentiation.

Human neural tube closure defects associated mutations in planar cell polarity (PCP) genes are causative of the disease, as revealed in the intricate Drosophila PCP model.

The Reissner fiber in the cerebrospinal fluid is required for a signal integrated by developing sensory neurons and modulated by catecholamines to control the embryo posterior axis morphogenesis.