Novel spatial representations by hippocampal cellular assemblies develop on the framework of preconfigured hippocampal networks whose homeostatic synaptic reorganization is accelerated by prior experience and CA3 NMDAR-dependent plasticity.
During learning, one climbing fiber input instructs plasticity that is expressed in the simple-spike responses of cerebellar Purkinje cells, and causes neural learning that may inhibit future climbing fiber instructions.
Jan Drugowitsch, Gregory C DeAngelis ... Alexandre Pouget
Through a combination of modeling and experiments it is shown that humans can near-optimally accumulate decision-related evidence across time and cues even when reaction time is under their control.
Felipe Mora-Bermúdez, Fumio Matsuzaki, Wieland B Huttner
Mammalian neural stem cells specifically regulate a subset of astral microtubules to govern the subtle changes in spindle orientation that underlie symmetric vs asymmetric cell division during embryonic cortical neurogenesis.
Neuroimaging provides novel insights into how the motor system represents sequences of actions by automatically separating their spatial and temporal features for flexible skill production.
Xueying Wang, John A Hayes ... Christopher A Del Negro
Laser-ablating neurons of a single genetic class reveals that Dbx1-derived interneurons comprise core respiratory rhythmogenic and premotor circuits and provides quantitative cellular parameters that govern network functionality
Output neurons in the mushroom body of the fruit fly brain encode the positive or negative survival value of stimuli, enabling insects to choose adaptive approach and avoidance behaviors through associative learning.
Angus Chadwick, Mark CW van Rossum, Matthew F Nolan
Independent coding without synaptic coordination explains complex sequences of population activity observed during theta states and maximizes the number of distinct environments that can be encoded through population theta sequences.
