Spatial genomics reveals the mode of evolution of a tumour based on the positions of mutations in high-resolution samples.

A 'male-harming' mtDNA mutation has been identified in Drosophila and impairs male fertility without impairing other male or female functions.

Gene expression and epigenetic profiling of defined cell types in the central nervous system of mouse, rat, and human reveals inter-species and inter-individual differences.

Integrated live cell imaging and image analyses in the framework of transition path theories identify epithelial-to-mesenchymal transition proceeds through parallel paths.

Normalizing Tcf4 expression during early postnatal development improves behavioral outcomes in Pitt-Hopkins syndrome (PTHS) model mice, suggesting that genetic therapies are feasible in individuals with PTHS.

The amyloid precursor protein known for its role in causing familial Alzheimer's disease directly interacts with secreted proteins, called Wnts, known for their key roles in brain development and homeostasis, suggesting the two processes may be directly linked.

Neuron type-specific gene batteries share cis-regulatory motifs.

New evidence for the impaired breathing activity is related to non-polyalanine repeat expansion mutations form of congenital central hypoventilation syndrome neuropathology.

Nuclei of the true slime mold Physarum polycephalum are continuously shuttled within the cytoplasmic flow across the gigantic syncytium, yet Physarum can establish and maintain gene expression heterogeneity between different structures of the organism.

Astrocytic G_i pathway activation in the anterior cingulate cortex impairs schema memory and neuronal mitochondrial biogenesis, which can be rescued by exogenous L-lactate administration directly into the area.