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The actomyosin network and phospho-regulation combine to polarize fate determinants at the Drosophila neuroblast cell cortex.

Characterization of an abundant clonogenic and multipotent population of immature neuroblasts, at the transition between transient-amplifying progenitor (TAP) neuroblasts and migratory neuroblasts, reversibly engaged in neuronal differentiation.

About twenty temporal patterning genes are identified that drive an irreversible differentiation trajectory governing the heterogeneity and proliferative properties of cells in neural tumors with an early developmental origin.

Large-scale changes in the brain's functional circuitry can be brought about by simple changes in gene expression in neural stem cells during development.

The Drosophila equivalent of the human protein Mixed Lineage Leukemia 1n enables neural stem cells to generate neural progenitors through the fly equivalent of the human transcription factor Sp8, thereby contributing to an increased number and diversity of cell types during brain development.

Cell-cycle-dependent Notch signaling cooperates with temporal transcription factors to promote the progression of the temporal transcription factor cascade in Drosophila medulla neuroblasts.

Mapping individual neural stem cells to their corresponding embryonic and postembryonic progeny shows that these sets of neurons have profound molecular and anatomical similarities despite building different central nervous systems.

The technique of serial blockface scanning electron microscopy, which permits the complete reconstruction of neuronal structures, allows comparison of the detailed "wiring diagrams" of lateral-line receptor organs in wild-type and mutant zebrafish.

A genetic method allows neurons to be individually identified and characterized by combining information about both their developmental origins and their mature patterns of gene expression.

Silencing of stem cell identity genes during progenitor commitment ensures that intermediate progenitors robustly commit to generate differentiated cell types rather than abnormal stem-cell-like cells during indirect neurogenesis.