The midbrain area for salience, reward and aversion in mouse brain harbours among the dopamine cells three subtypes somatostatin-expressing neurons that show combinatorial neurotransmitter phenotypes and interneuron properties.

The higher amount of cortical immature neurons in brains with expanded neocortices may represent a reservoir of young cells for mammals with reduced neurogenesis.

A provoked awakening protocol during sleep reveals that selective bilateral hippocampal damage in humans is associated with reduced frequency, quality, and content of dreaming.

Inhibition of the integrated stress response restores neuronal and immune dysfunction and alleviates memory deficits in aged mice.

The dorsal raphe nucleus contains transcriptionally diverse cell classes that include subtypes of serotonergic neurons with distinct molecular and anatomical signatures.

Clarinet, a novel C. elegans active zone protein with homology to vertebrate Piccolo and Rim, uses its different isoforms for diverse functions, including synaptic vesicle clustering, vesicle release and synaptogenesis.

Perirhinal cortex, a brain structure located in the medial temporal lobe, uniquely supports the integration of visual and conceptual object information.

Transcription factors KLF2 and ETV1 repress the transcriptional program of mitochondrial biogenesis, resulting in impaired mitochondrial function in lysosomal storage diseases.

Excitotoxicity driven by NMDA receptor hyper-activation does not involve DAPK1-dependent events in vitro or in vivo, and previously described DAPK1-NMDAR disrupting peptides act by blocking the NMDA receptor.

Computational modeling of the brain’s navigation system reveals that place cells can drive the formation of hexagonal patterns experimentally observed in grid cells activity.