Mice that lack the autism- and schizophrenia-linked gene MEF2C in cortical neurons have an imbalance of excitatory and inhibitory synapses, and impaired social and cognitive abilities.

Diffusion-MRI-based cerebral cortical microstructure encoding regionally differential dendritic arborization and synaptic formation at birth robustly predicts future 2-year-old cognitive and language outcomes with regionally heterogeneous contribution that exhibits functional selectivity.

Chronic dysregulation of matrix-metalloproteinase 9, which is associated with some neurodevelopmental disorders, leads to local hyperconnectivity in the developing brain, resulting in altered sensory processing and increased seizure susceptibility.

lnc-Nr2f1, a long non-coding RNA focally deleted in autism patients, directly occupies and regulates neuronal genes.

Identification of the underlying molecular gene-regulatory mechanisms by which the histone deacetylase complex MiDAC controls neurite outgrowth.

The ATP7A interactome is the first comprehensive view of putative Menkes disease neurodegeneration mechanisms.

Disruption of quality control pathways that function at distinct steps to mitigate errors in translation evoke similar cellular responses and pathologies.

Mid-gestational exposure to maternal immune activation drives a sequence of transcriptional signatures and developmental pathology in embryonic mouse cortex, culminating in altered lamination and cellular lineage specification.

Loss of function of the selective autophagy adaptor protein Alfy/Wdfy3 leads to profound wiring defects from the forebrain through to the spinal cord, highlighting the growing importance for macroautophagy in the developing brain.

The histone demethylase KDM5 functions in concert with the transcription factor Prospero to regulate a gene expression program that is required for mushroom body neuroanatomical development.