22 results found
    1. Computational and Systems Biology
    2. Neuroscience

    Uncovering the computational mechanisms underlying many-alternative choice

    Armin W Thomas et al.
    A comparison of different computational models reveals that looking behavior, during value-based choices from 9, 16, 25, or 36 snack foods, actively influences the subjective values of the available alternatives.
  1. Food for thought: an interview with Ana Domingos

    Ana Domingos of the Gulbenkian Science Institute in Portugal has forged a career learning why we like certain types of food. By looking at the reward system of the mouse brain, she has revealed pathways that explain why animals prefer sugar, and perhaps why it may factor so strongly in the Western diet.
    1. Neuroscience

    Capturing the temporal evolution of choice across prefrontal cortex

    Laurence T Hunt et al.
    Experiments in macaques and humans reveal time-varying changes in prefrontal cortex activity that occur during decisions based on costs and benefits.
    1. Neuroscience

    Value signals guide abstraction during learning

    Aurelio Cortese et al.
    Valuation of sensory information in the ventromedial prefrontal cortex plays a key function in constructing the abstract representations that guide complex behaviours.
    1. Neuroscience

    Alpha oscillations and event-related potentials reflect distinct dynamics of attribute construction and evidence accumulation in dietary decision making

    Azadeh HajiHosseini, Cendri A Hutcherson
    Alpha oscillations represent an intermediate stage of evidence accumulation that is influenced by self-regulation in value-based decision making.
    1. Neuroscience

    One-shot learning and behavioral eligibility traces in sequential decision making

    Marco P Lehmann et al.
    Human learning relies on short-term memories (eligibility traces) which provide a mechanism to reinforce sequences of actions from a single reward (one-shot).
    1. Neuroscience

    How prior preferences determine decision-making frames and biases in the human brain

    Alizée Lopez-Persem et al.
    Model-based analyses of choice behavior and fMRI activity revealed that prior preferences generate default policies, which frame the decision value signal encoded in the vmPFC, and shift vmPFC pre-choice activity so as to induce a decision bias toward default options.
    1. Neuroscience

    The dorsomedial prefrontal cortex computes task-invariant relative subjective value for self and other

    Matthew Piva et al.
    Activity in the dorsomedial prefrontal cortex encodes relative subjective value in a common neural code across decision-making for self and other and across tasks with divergent cognitive requirements.
    1. Neuroscience

    Mediodorsal thalamus is required for discrete phases of goal-directed behavior in macaques

    Evan Wicker et al.
    Transient suppression of activity in the macaque mediodorsal thalamus impairs adjustment of secondary reinforcer values and disrupts appropriate action selection in a reinforcer devaluation task; this profile is distinct from that of amygdala or subregions of orbitofrontal cortex.
    1. Neuroscience

    Medial orbitofrontal inactivation does not affect economic choice

    Matthew PH Gardner et al.
    Inactivation of the medial orbitofrontal cortex using an optogenetic approach did not affect behavior in rats on an iconic economic choice task.

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