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    1. Developmental Biology
    2. Neuroscience

    MiRNA-128 regulates the proliferation and neurogenesis of neural precursors by targeting PCM1 in the developing cortex

    Wei Zhang, Paul Jong Kim ... Li Zeng
    During early cortical development, microRNA-128 regulates the homeostasis of neural stem cells by targeting PCM1, a protein that is critical for cell division.
    1. Neuroscience

    Shh from mossy cells contributes to preventing NSC pool depletion after seizure-induced neurogenesis and in aging

    Hirofumi Noguchi, Jessica Chelsea Arela ... Samuel Pleasure
    Hilar mossy cells control seizure-dependent dentate neurogenesis and stem cell quiescence by activity-dependent control of Sonic hedgehog production and signaling.
    1. Developmental Biology
    2. Neuroscience

    A cellular and molecular analysis of SoxB-driven neurogenesis in a cnidarian

    Eleni Chrysostomou, Hakima Flici ... Uri Frank
    SoxB genes are sequentially expressed in cnidarian neurogenesis.
    1. Developmental Biology

    A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development

    Kerstin Hasenpusch-Theil, Christine Laclef ... Thomas Theil
    Primary-cilia-mediated processing of the Gli3 transcription factor enables the formation of subtypes of projection neurons in appropriate numbers during the development of the cerebral cortex.
    1. Neuroscience

    Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice

    Hongsheng Zhang, Anupama Sathyamurthy ... Lin Mei
    Enriched environment stimulates neuron generation in the hippocampus by a novel pathway involving Agrin, Lrp4, and Ror2.
    1. Computational and Systems Biology
    2. Neuroscience

    A functional model of adult dentate gyrus neurogenesis

    Olivia Gozel, Wulfram Gerstner
    The GABA input switching from excitatory to inhibitory during maturation of adult-born dentate granule cells is crucial for their integration into the preexisting circuit.
    1. Neuroscience

    A sleep state in Drosophila larvae required for neural stem cell proliferation

    Milan Szuperak, Matthew A Churgin ... Matthew S Kayser
    A role for sleep in developmental neurogenesis is revealed using a new system for studying sleep during nascent periods.
    1. Neuroscience
    2. Stem Cells and Regenerative Medicine

    AAV ablates neurogenesis in the adult murine hippocampus

    Stephen Johnston, Sarah L Parylak ... Matthew Shtrahman
    Future work using recombinant AAV as an experimental tool in the dentate gyrus or as a gene therapy for diseases of the central nervous system should be carefully evaluated.
    1. Cell Biology
    2. Stem Cells and Regenerative Medicine

    Environmental changes in oxygen tension reveal ROS-dependent neurogenesis and regeneration in the adult newt brain

    L Shahul Hameed, Daniel A Berg ... András Simon
    Control of neural stem cells by reactive oxygen species (ROS) provides a link between systemic shifts in oxygen tension and neuronal regeneration, and suggests an evolutionary driving force for the inherent ability of newts to regenerate their brain cells.
    1. Developmental Biology
    2. Neuroscience

    Ngn1 inhibits astrogliogenesis through induction of miR-9 during neuronal fate specification

    Jing Zhao, Quan Lin ... Yi Sun
    During neurogenesis, Neurogenin 1 activates the microRNA miR-9, which directly targets the Jak-Stat pathway to inhibit astrogliogenesis.