268 results found
    1. Neuroscience

    Neuromodulatory connectivity defines the structure of a behavioral neural network

    Feici Diao et al.
    Using targeted functional manipulations of neural activity to map neuromodulatory connections can deliver considerable insight into the functional architecture of a behaviorally important network even in the absence of information about its synaptic connectivity.
    1. Neuroscience

    Sequential neuromodulation of Hebbian plasticity offers mechanism for effective reward-based navigation

    Zuzanna Brzosko et al.
    Sequential neuromodulation by acetylcholine and dopamine enables correlational synaptic learning which, when incorporated into a computational model, yields effective navigation toward changing reward locations as in natural foraging behavior.
    1. Neuroscience

    HCN channel-mediated neuromodulation can control action potential velocity and fidelity in central axons

    Niklas Byczkowicz et al.
    The cAMP-HCN pathway can control action potential conduction velocity providing neuromodulators with the ability to tune energy consumption and temporal delays across axons in the brain.
    1. Neuroscience

    Synaptic transmission parallels neuromodulation in a central food-intake circuit

    Philipp Schlegel et al.
    Connectomic analysis demonstrates that a brain circuit, that may be conserved between flies and mammals, uses both fast synaptic transmission as well as peptidergic neuromodulation to connect chemosensory and endocrine systems.
    1. Neuroscience

    An extrasynaptic GABAergic signal modulates a pattern of forward movement in Caenorhabditis elegans

    Yu Shen et al.
    The activity of a set of GABAergic neurons is causally linked with a locomotory pattern in moving animals, and the mechanisms underlying the neuromodulatory role of GABA are illuminated.
    1. Neuroscience

    Cellular and neurochemical basis of sleep stages in the thalamocortical network

    Giri P Krishnan et al.
    A computational model of the thalamocortical network explains sleep stages by the coordinated variations in the level of neuromodulators and predicts differences of sleep pattern in human, cat and mouse recordings.
    1. Neuroscience

    Control of entropy in neural models of environmental state

    Timothy H Muller et al.
    Evidence for neuromodulatory control of flexibility in human neural models.
    1. Neuroscience

    Starvation promotes concerted modulation of appetitive olfactory behavior via parallel neuromodulatory circuits

    Kang I Ko et al.
    Starvation upregulates activity in certain sensory channels and downregulates it in others in what appears to be an optimization strategy that serves to increase the hedonic value of food odors.
    1. Neuroscience

    Neuromodulation of excitatory synaptogenesis in striatal development

    Yevgenia Kozorovitskiy et al.
    Protein kinase A regulates the rapid, activity-dependent genesis of excitatory synapses during striatal development.
    1. Developmental Biology
    2. Neuroscience

    Stereotyped responses of Drosophila peptidergic neuronal ensemble depend on downstream neuromodulators

    Wilson Mena et al.
    The response of the peptidergic neurons that control a stereotyped behavior depends on the actions of a triggering neuropeptide, downstream neuropeptides and GABA inhibitory influences.

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