4,830 results found
    1. Neuroscience

    Social aversive generalization learning sharpens the tuning of visuocortical neurons to facial identity cues

    Yannik Stegmann et al.
    Measures of visuocortical activity during aversive generalization learning revealed sharpened representations of facial identity, reflecting inhibitory interactions between neuronal populations that represent facial features associated with threat versus safety.
    1. Developmental Biology
    2. Neuroscience

    Establishment and maintenance of motor neuron identity via temporal modularity in terminal selector function

    Yinan Li et al.
    The terminal selector-type transcription factor UNC-3/Ebf partially modifies the suite of its target genes at different life stages to establish and maintain the identity of C. elegans motor neurons.
    1. Developmental Biology
    2. Neuroscience

    Identity of neocortical layer 4 neurons is specified through correct positioning into the cortex

    Koji Oishi et al.
    Layer 4 neuronal identity is specified by Protocadherin20 positioning the neurons into layer 4 so that they receive a positional cue from thalamocortical axons.
    1. Developmental Biology
    2. Neuroscience

    Temporal identity establishes columnar neuron morphology, connectivity, and function in a Drosophila navigation circuit

    Luis F Sullivan et al.
    The Eyeless/Pax6 temporal transcription factor generates neuronal identity, connectivity, and flight navigation behavior within the conserved adult brain structure called the central complex.
    1. Developmental Biology
    2. Neuroscience

    The transcription factor odd-paired regulates temporal identity in transit-amplifying neural progenitors via an incoherent feed-forward loop

    Merve Deniz Abdusselamoglu et al.
    Odd-paired (opa) is required for the progression of temporal patterning in Drosophila neural progenitors to regulate temporal identities via an incoherent feed-forward loop.
    1. Developmental Biology
    2. Neuroscience

    A terminal selector prevents a Hox transcriptional switch to safeguard motor neuron identity throughout life

    Weidong Feng et al.
    A molecular mechanism that involves highly conserved transcription factors enables cholinergic motor neurons of the nematode Caenorhabditis elegans to become and remain functional.
    1. Neuroscience

    Embryonic transcription factor expression in mice predicts medial amygdala neuronal identity and sex-specific responses to innate behavioral cues

    Julieta E Lischinsky et al.
    Studying the development of the medial amygdala in the mouse reveals how the brain may potentially process sex differences in innate behaviors such as mating.
    1. Computational and Systems Biology
    2. Neuroscience

    Training deep neural density estimators to identify mechanistic models of neural dynamics

    Pedro J Gonçalves et al.
    Deep neural networks can be trained to automatically find mechanistic models which quantitatively agree with experimental data, providing new opportunities for building and visualizing interpretable models of neural dynamics.
    1. Developmental Biology
    2. Neuroscience

    Dlk1-Dio3 locus-derived lncRNAs perpetuate postmitotic motor neuron cell fate and subtype identity

    Ya-Ping Yen et al.
    LncRNAs are important to stabilize postmitotic cell fate of spinal motor neurons.
    1. Neuroscience

    Odor identity coding by distributed ensembles of neurons in the mouse olfactory cortex

    Benjamin Roland et al.
    In vivo calcium imaging reveals how odor identity is encoded in the activity of large, distributed ensembles of olfactory cortex neurons in mice.

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