Timothy A Currier, Andrew MM Matheson, Katherine I Nagel
Electrophysiology identifies a population of fan-shaped body neurons that encode airflow in two directions relative to the fly midline and whose silencing disrupts proper orientation to airflow.
Malonyl-CoA, the rate-limiting substrate for fatty acid synthesis, is produced in the soma and delivered through gap junctions to the germline to promote reproduction and coordinate it with nutritional status.
Kirby M Donnelly, Olivia R DeLorenzo ... Margaret M Panning Pearce
Prion-like transfer of mutant huntingtin aggregates from presynaptic to postsynaptic neurons is enhanced by neuronal silencing and requires passage through the cytoplasm of Draper-expressing phagocytic glia in adult Drosophila brains.
Functional dissection of a cluster of male-specific neurons in Drosophila reveals a neuronal circuit regulating male courtship in accordance with the internal drive state.
Threonine promotes sleep via down-regulation of metabotropic GABA transmission in the ellipsoid body R2 neurons that generate homeostatic sleep drive in Drosophila.
An unbiased genetic screen in Drosophila provides evidence for a direct link between glial Ca2+ 25 signaling and classical functions of glia in buffering external K+ as a mechanism to regulate neuronal excitability.
Kathryn M Tabor, Gregory D Marquart ... Harold A Burgess
A new resource of transgenic zebrafish lines facilitates precise targeting of neuronal cell-types within the brain, supported by online software for visualizing transgene expression patterns.
Ourania Semelidou, Summer F Acevedo, Efthimios MC Skoulakis
Habituation to brief olfactory stimulation is biphasic and mediated by distinct neuronal circuits where an initial latency phase is rapidly followed by stimulus devaluation signifying behavioral habituation in Drosophila.
Ibrahim Tastekin, Avinash Khandelwal ... Matthieu Louis
The reconstruction of a sensorimotor pathway from the olfactory-sensory neurons down to the pre-motor system reveals a descending neuron that plays a critical role in the organization of larval chemotaxis.
Two different classes of taste receptor neurons in the Drosophila melanogaster proboscis play distinct roles in yeast feeding and are both modulated by the fly's internal amino acid state in order to promote protein-specific appetite.
