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First-order interneurons in the Drosophila visual system are not ON or OFF pathway-specific inputs, but serve as distinct computational units that distribute different kinds of luminance and contrast information across pathways to achieve stable behavioral responses to visual stimuli.

Increased Notch signaling enhances germ cell reprograming in C. elegans by antagonizing PRC2-mediated repression, which results in the activation of UTX-1 and other reprograming-promoting genes.

An unbiased genetic screen in Drosophila provides evidence for a direct link between glial Ca2+ 25 signaling and classical functions of glia in buffering external K+ as a mechanism to regulate neuronal excitability.

Functional dissection of a cluster of male-specific neurons in Drosophila reveals a neuronal circuit regulating male courtship in accordance with the internal drive state.

FlpStop is a generalizable tool for conditional gene disruption and rescue and enables critical experiments examining the interactions between genes, circuits, and computation.

Genetic experiments in zebrafish identify neuropeptide VF (NPVF) signaling and NPVF-expressing neurons as a novel vertebrate hypothalamic sleep-promoting system that is functionally conserved with invertebrates.

A fully automated workflow for high-throughput mouse behavioral and optogenetic experiments in homecage reveals involvement of brain regions in tactile decision-making.