4,676 results found
    1. Stem Cells and Regenerative Medicine

    The neural crest is a source of mesenchymal stem cells with specialized hematopoietic stem cell niche function

    Joan Isern et al.
    Developing long bones contain distinct mesenchymal stem-cell populations derived from mesoderm and neural crest, which have specialized functions in skeleton formation and the establishment of the hematopoietic stem-cell niche, respectively.
    1. Genetics and Genomics
    2. Neuroscience

    A genetic, genomic, and computational resource for exploring neural circuit function

    Fred P Davis et al.
    Transcriptomes of cells in the Drosophila visual system combined with anatomy and other information reveal new functional insight into the visual circuit.
    1. Developmental Biology
    2. Neuroscience

    Achieving functional neuronal dendrite structure through sequential stochastic growth and retraction

    André Ferreira Castro et al.
    An optimal wire and function trade-off emerges from noisy growth and stochastic retraction during Drosophila class I ventral posterior dendritic arborisation (c1vpda) dendrite development.
    1. Neuroscience

    Functional reallocation of sensory processing resources caused by long-term neural adaptation to altered optics

    Antoine Barbot et al.
    Chronic exposure to poor optical quality causes a functional reallocation of sensory processing resources that favors perceptual information less affected by the eye's optics.
    1. Neuroscience

    Structural and functional properties of a probabilistic model of neuronal connectivity in a simple locomotor network

    Andrea Ferrario et al.
    A new probabilistic model of connectivity reveals the structural and functional properties of the neural networks controlling locomotion in many individual tadpoles.
    1. Developmental Biology
    2. Neuroscience

    Comparison of induced neurons reveals slower structural and functional maturation in humans than in apes

    Maria Schörnig et al.
    Neurons mature slower in humans than in other non-human primates.
    1. Developmental Biology

    Neuron hemilineages provide the functional ground plan for the Drosophila ventral nervous system

    Robin M Harris et al.
    Hemilineages link neuronal stem cells to behavioral functions by providing a conserved ground plan of neuronal types that evolution then uses to sculpt different types of walking and flight behaviors.
    1. Neuroscience
    2. Structural Biology and Molecular Biophysics

    Kv2.1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons

    Nicholas C Vierra et al.
    A potassium channel, as a nonconducting function, organizes compartmentalized neuronal calcium signaling microdomains via structural and functional coupling of plasma membrane and endoplasmic reticulum calcium channels.
    1. Developmental Biology
    2. Genetics and Genomics

    Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism

    Samuel Andrew Malone et al.
    Mouse in vivo and in vitro analysis and human genetic screening highlight the role of anti-Müllerian hormone (AMH) signaling in GnRH neuronal development and function, and identify mutations in AMH and AMHR2 in CHH patients.
    1. Neuroscience

    Regulation of neuronal axon specification by glia-neuron gap junctions in C. elegans

    Lingfeng Meng et al.
    Genetic study of C. elegans neural development reveals the function of glia-neuron gap junctions in neuronal axon specification, and shows that glial cells regulate neuronal intracellular pathways through gap junctions.

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