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    1. Neuroscience

    Reward contingency gates selective cholinergic suppression of amygdala neurons

    Eyal Y Kimchi, Anthony Burgos-Robles ... Kay M Tye
    Electrophysiological recordings and optogenetic manipulations revealed the distinct roles that acetylcholine can have on the amygdala and prefrontal cortex in a Window of Opportunity Task.
    1. Neuroscience

    CA2 neuronal activity controls hippocampal low gamma and ripple oscillations

    Georgia M Alexander, Logan Y Brown ... Serena M Dudek
    Hippocampal area CA2 controls low gamma and ripple oscillations, brain waves known to be impaired in schizophrenia, implicating this important brain region in cognition.
    1. Neuroscience

    Optogenetically induced low-frequency correlations impair perception

    Anirvan Nandy, Jonathan J Nassi ... John Reynolds
    Low-frequency correlations among neurons in monkey visual area V4 impair the animal's ability to perform an attention-demanding task, suggesting a causal role of these fluctuations in perception.
    1. Neuroscience

    Transcranial magnetic stimulation (TMS) inhibits cortical dendrites

    Sean C Murphy, Lucy M Palmer ... Matthew E Larkum
    Studying the activity of cortical neurons in rats reveals the subcellular effects of transcranial magnetic stimulation, which is used for the non-invasive treatment of a variety of brain disorders.
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Altered temporal sequence of transcriptional regulators in the generation of human cerebellar granule cells

    Hourinaz Behesti, Arif Kocabas ... Mary E Hatten
    Human pluripotent stem cell modeling of the ATOH1 lineage identifies a temporal shift in the expression of key transcriptional regulators in the developing human cerebellum, this molecular divergence may drive the protracted development of the human cerebellum compared to rodents.
    1. Neuroscience

    Morphology and ultrastructure of external sense organs of Drosophila larvae

    Vincent Richter, Anna Rist ... Andreas S. Thum
    Revised
    Reviewed Preprint v2
    Updated
    • Fundamental
    • Compelling
    1. Neuroscience

    Medullary tachykinin precursor 1 neurons promote rhythmic breathing

    Jean-Philippe Rousseau, Andreea Furdui ... Gaspard Montandon
    A group of neurons in the medulla expressing the tachykinin precursor 1 promote rhythmic breathing, but also elicit substantial motor behaviors, suggesting a dual role for these neurons in the medulla.
    1. Developmental Biology
    2. Cancer Biology

    Dissecting infant leukemia developmental origins with a hemogenic gastruloid model

    Denise Ragusa, Chun-Wai Suen ... Cristina Pina
    Not revised
    Reviewed Preprint v1
    • Valuable
    • Inadequate
    1. Developmental Biology
    2. Stem Cells and Regenerative Medicine

    Direct lineage conversion of postnatal mouse cortical astrocytes to oligodendrocyte lineage cells

    Justine Bajohr, Erica Y Scott ... Maryam Faiz
    Not revised
    Reviewed Preprint v1
    • Useful
    • Solid
    1. Structural Biology and Molecular Biophysics
    2. Neuroscience

    Definition of two agonist types at the mammalian cold-activated channel TRPM8

    Annelies Janssens, Maarten Gees ... Thomas Voets
    Two natural cooling agents activate the cold-activated channel TRPM8 via two opposite mechanisms, evoking distinct electrical responses in cold-sensitive neurons.