Consolidation of long-term courtship memory in Drosophila is mediated by a novel class of sleep promoting neurons that reactivates dopaminergic neurons engaged earlier in memory acquisition during post-learning sleep.
Phasic activation of dorsal raphe serotonin neurons transiently inhibits locomotion without influencing anxiety or producing reinforcement, but when repeated over many days a long-term facilitation of locomotion is produced.
The Sip-Triggered Optogenetic Behavior Enclosure (STROBE) produces robust behaviors via activation of peripheral or central neurons in the fly, and mimics key features of feeding driven by chemical taste ligands.
Determining how GIRK2 activity depends on the concentration of Gβγ subunits in lipid membranes at different Na+ concentrations has allowed the Gβγ concentration generated during GABAB activation in neurons to be estimated.
During quiet wakefulness but not slow wave sleep, reward modulated VTA neurons coordinate selectively with hippocampal replay sequences and are biased in their timing towards the reactivated representation of reward locations.
In mouse models of Huntington's disease, striatal spiny projection neurons up-regulate dendritic potassium channels, which impairs their normal function, but a zinc finger gene therapy can reverse this deficit.