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Stem Cells and Regenerative Medicine
Neural stem cells induce the formation of their physical niche during organogenesis
Ali Seleit et al.
A physical niche for neural stem cells is generated by the induction of the immediate skin epithelium, a process triggered by the arrival of neural precursors during sensory organ formation in medaka.
Bright multicolor labeling of neuronal circuits with fluorescent proteins and chemical tags
Richi Sakaguchi et al.
A bright and stochastic multicolor labeling method, Tetbow, facilitates millimeters-scale reconstructions of neuronal circuits at a large scale using tissue clearing.
Monosynaptic tracing maps brain-wide afferent oligodendrocyte precursor cell connectivity
Christopher W Mount et al.
Oligodendrocyte precursor cells receive brain-wide, circuit-specific intracortical, coritcocortical and thalamocortical synaptic inputs.
Spinal microcircuits comprising dI3 interneurons are necessary for motor functional recovery following spinal cord transection
Tuan V Bui et al.
A genetically-defined population of spinal interneurons is reciprocally connected with spinal locomotor circuits and mediates recovery of locomotor function following spinal cord transection.
Area 2 of primary somatosensory cortex encodes kinematics of the whole arm
Raeed H Chowdhury et al.
Area 2 of somatosensory cortex represents kinematic details of the entire arm during movement, but this mapping from limb state to neural activity differs for reaching and passive limb displacement.
Structural Biology and Molecular Biophysics
MeCP2 nuclear dynamics in live neurons results from low and high affinity chromatin interactions
Francesco M Piccolo et al.
Single molecular imaging of MeCP2 at high spatial/temporal resolution identifies distinct structural domains contributing to its dynamic behaviors and chromatin interactions in live neurons.
Balancing model-based and memory-free action selection under competitive pressure
Atsushi Kikumoto, Ulrich Mayr
People compete by trying to outsmart their opponents as long as they win, but show random behavior, and neural signs of suppressing knowledge about opponents’ strategies, when they lose.
The recovery of standing and locomotion after spinal cord injury does not require task-specific training
Jonathan Harnie et al.
Restoring locomotion after complete spinal cord injury does not require locomotor training, only the return of sufficient excitability within neurons of the spinal cord.
Rapid whole brain imaging of neural activity in freely behaving larval zebrafish (
Lin Cong et al.
The integration of a novel high spatiotemporal resolution volume imaging technique and a fast 3D tracking system allows capturing whole brain neural activities in a freely behaving larval zebrafish.
Dopaminergic modulation of the exploration/exploitation trade-off in human decision-making
Karima Chakroun et al.
Dopamine attenuates exploration during decision-making via a reduction of neural tracking of uncertainty.
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