1,551 results found
    1. Neuroscience

    A Statistical Framework for Analysis of Trial-Level Temporal Dynamics in Fiber Photometry Experiments

    Gabriel Loewinger, Erjia Cui ... Francisco Pereira
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Convincing
    1. Neuroscience

    An Information-Theoretic Approach to Reward Rate Optimization in the Tradeoff Between Controlled and Automatic Processing in Neural Network Architectures

    Giovanni Petri, Sebastian Musslick, Jonathan D. Cohen
    Not revised
    Reviewed Preprint v1
    • Useful
    • Incomplete
    1. Cell Biology
    2. Microbiology and Infectious Disease

    Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma

    Alex W Chan, Malgorzata Broncel ... Sebastian Lourido
    Comprehensive characterization of kinase-dependent phosphorylation in the human pathogen Toxoplasma gondii identifies a trafficking adaptor complex required for virulence factor secretion and infection.
    1. Neuroscience
    2. Computational and Systems Biology

    A stochastic model of hippocampal synaptic plasticity with geometrical readout of enzyme dynamics

    Yuri Elias Rodrigues, Cezar M Tigaret ... Romain Veltz
    A computational model of glutamatergic synapse uncovers a new plasticity rule which takes into account the various experimental conditions.
    1. Computational and Systems Biology
    2. Neuroscience

    Natural-gradient learning for spiking neurons

    Elena Kreutzer, Walter Senn, Mihai A Petrovici
    A parametrization-invariant synaptic plasticity rule based on natural-gradient descent leads to multiple predictions for the biological plasticity process, some of which relate to well-studied phenomena such as heterosynaptic plasticity.
    1. Developmental Biology
    2. Neuroscience

    Diversification of multipotential postmitotic mouse retinal ganglion cell precursors into discrete types

    Karthik Shekhar, Irene E Whitney ... Joshua R Sanes
    Single-cell transcriptomic analysis of developing retinal ganglion cells in mice suggests that their diversification into 45 discrete types occurs via the gradual restriction of multipotential precursors.
    1. Developmental Biology
    2. Neuroscience

    Chronology-based architecture of descending circuits that underlie the development of locomotor repertoire after birth

    Avinash Pujala, Minoru Koyama
    Newly forming descending pathways are arranged to function in parallel to existing ones and contribute to increasingly sophisticated locomotor behaviors that emerge postnatally with suitable connectivity patterns and biophysical properties.
    1. Neuroscience

    Specific presynaptic functions require distinct Drosophila Cav2 splice isoforms

    Christopher Bell, Lukas Kilo ... Stefanie Ryglewski
    Revised
    Reviewed Preprint v2
    Updated
    • Important
    • Solid
    1. Neuroscience

    Data-driven reduction of dendritic morphologies with preserved dendro-somatic responses

    Willem AM Wybo, Jakob Jordan ... Walter Senn
    A flexible and accurate methodology to fit reduced compartmental models to dendritic morphologies shows that models with very few compartments can capture many dendritic computations.
    1. Neuroscience

    The effects of chloride dynamics on substantia nigra pars reticulata responses to pallidal and striatal inputs

    Ryan S Phillips, Ian Rosner ... Jonathan E Rubin
    The effects of chloride homeostasis can explain diverse responses of basal ganglia output neurons to putatively inhibitory inputs and may tune these neurons' synchrony, oscillations and behavior in decision-making scenarios.

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