Browse the search results

Neurotransmitter balance in a region in frontal cortex controls how much people use information they have learnt to guide their behaviour.

Two different binding modes of the Munc13-1 C­₁C₂B region govern synaptic vesicle priming and neurotransmitter release probability.

A model for synchronous neurotransmitter release suggests that when not in the presence of calcium ions, Synaptotagmin proteins form ring-like structures between the vesicle and plasma membrane that prevent spontaneous fusion.

Extensive mass spectrometry-based profiling of polar metabolites within synaptic vesicles that are rapidly isolated either from cultured mouse neurons or directly from mouse brains reveals their neurotransmitter composition.

Retinal waves are correlated with calcium transients in Müller cells, demonstrating that spontaneous activity encompasses both neuronal and glial networks during a crucial period of retinal development.

Cryo-electron tomography, reconstitution, and electrophysiological data show that a fundamental function of Munc13-1 is to bridge synaptic vesicles to the presynaptic plasma membrane.

A range of experiments suggests that creatine, a molecule known for recycling ATP in muscle and brain tissue, may also function as a neurotransmitter in the central nervous system.

A G protein in striatal neurons forms preassembled complexes with its downstream enzyme, adenylyl cyclase, which has implications for the pathophysiology of movement disorders.

The Kv3.3 potassium channel subunit is necessary and sufficient to permit presynaptic location and accelerated repolarisation of the presynaptic action potential, thereby conserving resources and enhancing accuracy of timing information on transmission at the calyx of Held excitatory synapse.

Dopamine release within the mouse external globus pallidus, an area of very sparse innervation, is observed and described for the first time through a new technique: flashing false fluorescent neurotransmitters.